加减橘核丸联合迈之灵治疗慢性附睾炎  

Clinical Research of JuHe Decoction Combined with Aescuvenforte Tablets in Treatment of Chronic Epididymitis

作　　者：夏国守[1] 孙大林[2] 金保方[2] 

机构地区：[1]南京中医药大学第三附属医院男科,南京210001 [2]东南大学附属中大医院中西医结合男科,南京210009

出　　处：《中国中西医结合外科杂志》2017年第5期471-474,共4页Chinese Journal of Surgery of Integrated Traditional and Western Medicine

基　　金：国家自然科学青年基金(81403402);国家自然科学基金(81473678)

摘　　要：目的:探讨加减橘核丸联合迈之灵治疗慢性附睾炎的临床疗效。方法:选择慢性附睾炎患者81例,随机分成对照组(33例)和治疗组(48例);对照组口服左氧氟沙星,治疗组口服中药橘核丸加减联合迈之灵片。治疗前和治疗后4周分别评价慢性附睾炎症状指数评分(CESI)、疼痛评分、生活质量评分、CESI总分,统计临床疗效。结果:对照组治疗前后CESI疼痛评分(7.79±1.73,5.52±1.15)、生活质量评分(7.97±1.76,6.55±1.23)、CESI总分(15.36±3.41,12.06±2.18)均有下降,CESI总分较治疗前有统计学差异(P<0.05);治疗组治疗前后CESI疼痛评分(7.60±1.47,3.31±2.02)、生活质量评分(8.13±1.44,3.94±2.50)、CESI总分(15.73±2.65,7.25±4.39)均有显著下降(P<0.05),并优于对照组(P<0.05),治疗组显效率(70.83%)和总有效率(87.5%)均优于对照组显效率(18.18%)和总有效率(52%)(P<0.05)。结论:加减橘核丸联合迈之灵治疗慢性附睾炎临床疗效显著。Objective To investigate the curative effect of JuHe Decoction combined with Aescuvenforte Tablets in the treatment of chronic epididymitis. Methods Eighty-one cases of chronic epididymitis were se- lected and assigned randomly into control group （33 cases） and treatment group （48 cases）. The control group re- ceived levofloxacin treatment. Meanwhile, the treatment group received JuHe Decoction combined with Aescuven- forte Tablets. Before and after 4 weeks of treatment, the scores of Chronic Epididymitis Symptom Index （CESI）, quality of life, CESI total scores were detected. And the clinical efficiency was calculated. Results Compared with pretherapy, all the scores were decreased in the control group after 4 weeks, including the scores of CESI pain （7.79±1.73, 5.52±1.15）, quality of life（7.97±1.76,6.55±1.23）, total scores（15.36±3.41, 12.06±2.18）. And the CESI total scores had a statistics difference compared to pre-treatment （P 〈 0.05）. While the scores after 4 weeks in the treatment group were remarkably lower than the pretherapy, including the pain scores of CESI （7.60± 1.47, 3.31 ±2.02）, quality of life scores （8.13± 1.44, 3.94±2.50）, CESI total scores （ 15.73±2.65,7.25± 4.39）. The effectiveness in treatment group was better than that in the control group （P 〈 0.05）. Besides, the ex- cellence rate （70.83%） and total efficiency （87.5%） of the treatment group were better than the excellence rate （18.18%） and total efficiency （52%） of control group （P 〈 0.05）. Conclusion JuHe Decoction combined with Aescuvenforte Tablets shows significant efficacy on chronic epididymitis.

关 键 词：橘核丸 迈之灵 慢性附睾炎 症状指数评分 

分 类 号：R697.22[医药卫生—泌尿科学]