小儿热速清颗粒联合利巴韦林治疗手足口病的临床观察  

Clinical observation of Resuqing Granules for children combined with Ribavirin in the treatment of hand-foot-mouth diseases

作　　者：郑根霖 吕述华[1] 康锋[2] 

机构地区：[1]江西省遂川县人民医院感染科,江西遂川343900 [2]江西省遂川县人民医院肾内科,江西遂川343900

出　　处：《中国当代医药》2017年第28期132-134,共3页China Modern Medicine

摘　　要：目的探讨小儿热速清颗粒联合利巴韦林治疗手足口病的临床效果。方法选取2015年11月~2016年11月在我院进行治疗手足口病的80例患儿作为研究对象,将其按照随机数表法分为观察组和对照组,每组各40例。对照组患儿选择利巴韦林进行治疗,观察组患儿在此基础上结合小儿热速清颗粒进行治疗。观察比较两组患儿的皮疹消失时间、退热时间、治疗效果等相关指标。结果观察组患儿的皮疹消失时间、退热时间、痊愈时间分别为[(3.78±1.61)d、(2.42±0.32)d、(5.28±1.37)d],均显著优于对照组[(6.15±1.53)d、(4.63±1.12)d、(7.43±1.13)d],差异有统计学意义(P<0.05)。观察组的治疗总有效率(95.0%)高于对照组(77.5%),差异有统计学意义(P<0.05)。结论在采用利巴韦林治疗的基础上结合小儿热速清颗粒对手足口病进行治疗,能够缩短退热时间,改善临床症状,缩短病程,拥有更好的疗效和更高的安全性,值得在临床中推广应用。Objective To explore the clinical effect of Resuqing Granules for children combined with Ribavirin in the treatment of hand-foot-mouth diseases.Methods 80 children with hand-foot-mouth diseases treated in our hospital from November 2015 to November 2016 were selected as subjects.By a random number table,they were evenly divided into observation group and control group,40 cases in each group.The children in the control group were treated with Ribavirin,and the children in the observation group were treated with Resuqing Granule on the base of Ribavifin.The related indicators including the disappearing time of rash,fever-abating time and therapeutic effect of the two groups were observed and compared.Results In the observation group,the disappearing time of rash,fever-abating time and healing time were respectively [（3.78±1.61）d,（2.42±0.32）d, （5.28±l.37）d],which were much better than those in the con- trol group [（6.15±1.53）d,（4.63±1.12）d,（7.43±1.13）d],and the differences were statistically significant （P〈0.05）.The total effective rate in the observation group （95%） was higher than that in the control group （77.5%）,and the difference was statistically significant （P〈0.05）.Conclusion On the basis of Ribavirin,Resuqing Granule in the treatment of hand-foot- mouth diseases can shorten the time of abating fever,improve clinical symptoms,shorten the course of disease in high efficacy and safety,which is worthy of promotion and application.

关 键 词：利巴韦林 手足口病 病毒 感染 呼吸衰竭 

分 类 号：R473.72[医药卫生—护理学]