脑忆清胶囊对小鼠免疫功能的影响  

Effect of NaoyiQing Capsule on Immune Function in Mice

作　　者：陈勤[1] 曹炎贵[1] 

机构地区：[1]安徽大学生命科学学院,合肥230039

出　　处：《中国现代应用药学》2002年第4期260-261,共2页Chinese Journal of Modern Applied Pharmacy

基　　金：国家药品监督局新药管理中心青年科研基金资助课题 ( 95 -Q -0 9)

摘　　要：目的 :观察脑忆清胶囊对小鼠免疫功能的影响。方法 :采用显微镜观察腹腔巨噬细胞的吞噬百分率和吞噬指数 ,用分光光度测定血清溶血素含量 ,用3 H TdR掺入法测定脾细胞淋巴细胞增殖率。结果 :脑忆清胶囊能明显增加正常小鼠腹腔巨噬细胞的吞噬百分率及吞噬指数 ,显著拮抗环磷酰胺所致免疫功能低下小鼠的免疫器官重量减轻 ,显著增加血清溶血素含量 ,且能明显促进ConA诱导的脾T淋巴细胞增殖反应。结论OBJECTIVE:To observe the effect of Naoyiqing capsule on immune function in mice. METHOD:Phagocytic percentage and phagocytic index in peritoneal macrophages (PMφ) were observed by microscope, content of serum hemolysin was determined by spectrophotography, and proliferative rate of lymphocyte within the splenocyte was detected by 3H TdR dope method. RESULTS:Naoyiqing capsule significantly increased Phagocytic percentage and phagocytic index in PMφ of normal mice, obviously antagonized the immune organ weight loss induced by cyclophosphamide (Cy) and markedly increased the contents of serum hemolysin and obviously promoted proliferative response of splenic T lymphocyte induced by ConA.CONCLUSION:These results suggested that Naoyiqing capsule significantly improved immune function in mice.

关 键 词：脑忆清胶囊 免疫功能 小鼠 中药 药理 

分 类 号：R285.5[医药卫生—中药学]