仙草风湿胶囊中吲哚美辛和吡罗昔康的含量测定  

Determination of Indometacin and Piroxicam in Xianchao Fengshi Capsules

作　　者：鲁秋红[1] 符洪[1] 谢世祺 

机构地区：[1]海南省药品检验所,海口570102

出　　处：《中国现代应用药学》2002年第4期319-320,共2页Chinese Journal of Modern Applied Pharmacy

摘　　要：目的 :采用双波长分光光度法和单波长分光光度法测定仙草风湿胶囊中吲哚美辛和吡罗昔康的含量。方法 :利用吲哚美辛和吡罗昔康溶解性能 ,采用氯仿溶解 ,碱液提取 ,用双波长分光光度法和单波长分光光度法 ,分别测定吲哚美辛和吡罗昔康的含量。结果 :吲哚美辛和吡罗昔康的平均回收率分别为 99.7%和 10 0 .7% ,RSD分别为 0 .72 %和 0 .86 %。结论 :方法简便 ,可靠 ,重现性好 。OBJECTIVE:To establish a method for the determination of Indometacin and Piroxicam in Xianchao Fengshi Capsules by dual wavelength and single wavelength UV. METHOD:To make use of solubility of Indometacin and Piroxicam, The sample was dissolved with chloroform and extracted with solution of 0.1mol·L 1 sodium Hydroxide. Indometacin and Piroxicam were separately measured by dual wavelength and single wavelength UV spectrophotometry.RESULTS:The average recovery were 99.7% and 100.7% for Indometacin and Piroxicam, respectively. The RSD were 0.72% and 0.86% for Indometacin and Piroxicam, respectively.CONCLUSION:This method is simple, reliable, reproducible and eliminate disturbance of chinese herbal medicine composition.

关 键 词：含量 测定 吲哚美辛 吡罗昔康 双波长分光光度法 单波长分光光度法 

分 类 号：R284.1[医药卫生—中药学]