基于五味子酯甲含量分析南五味子药材商品规格等级  

Analysis of commercial grades of Schisandrae Sphenantherae Fructus based on schisantherin

作　　者：王振恒[1,2,3] 晋玲 马毅[1,2,3] 崔治家 李倩[1] 黄得栋 

机构地区：[1]甘肃中医药大学,甘肃兰州730000 [2]中(藏)药资源研究所,甘肃兰州730000 [3]甘肃省高校中(藏)药化学与质量研究省级重点实验室,甘肃兰州730000

出　　处：《中国中药杂志》2017年第19期3728-3732,共5页China Journal of Chinese Materia Medica

基　　金：中央本级重大增减支项目(2060302);中央引导地方科技发展专项;甘肃省基础研究创新群体项目(1606RJIA323)

摘　　要：收集不同产地南五味子药材进行等级划分,采用药典方法进行水分、总灰分的测定,采用UPLC测定五味子酯甲含量进测定,确定南五味子商品等级划分和五味子酯甲之间的关系。结果表明不同产地的南五味子药材水分、总灰分及五味子酯甲含量均合格。不同等级间的南五味子药材五味子酯甲的含量无显著差异,但是二等品含量最高,三等品、一等品含量低,等级与五味子酯甲的含量不成正相关关系。该研究结果对于南五味药材的生产经营和质量评价具有一定指导意义。Schisandrae Sphenantherae Fructus,from different producing areas,were collected and divided into three grades. The moisture content and total ash were determined on the basis of the pharmacopoeia method,and schisantherin was determined by UPLC.The study is aimed to find the commercial specifications and grades of Schisandrae Sphenantherae Fructus based on schisantherin content. The results showed that the content of water,total ash and schisantherin of Schisandrae Sphenantherae Fructus from different producing areas qualified. There was no significant difference between different grades of schisandrin content,but the second-class were the highest,first-class and third-class were lower. It means that schisandrin content is not positive correlation to commercial grade. The study will be helpful to the production,management and clinical practice of Schisandrae Sphenantherae Fructus.

关 键 词：南五味子 商品规格等级 五味子酯甲 超高效液相色谱法 

分 类 号：R284.1[医药卫生—中药学]