河北省沧州市城镇居民健康体检者甲状腺功能异常分析  

Analysis of abnormal thyroid function in the health check-ups of residents in Cangzhou City of Hebei Province

作　　者：侯振江[1] 牟兆新[1] 张靖宇[2] 范洪 王华新[3] 

机构地区：[1]河北省沧州医学高等专科学校甲状腺疾病研究所,沧州061001 [2]河北省沧州中西医结合医院实验诊断科,沦州061001 [3]河北省黄骅开发区博爱医院,黄骅061100

出　　处：《中华地方病学杂志》2017年第10期764-767,共4页Chinese Journal of Endemiology

基　　金：沧州医学高等专科学校自然科学课题（142001）;河北省科技计划基金项目（15277796D）

摘　　要：目的了解沧州市城镇居民健康人群甲状腺功能的异常情况，为减少甲状腺疾病的发生提供参考。方法选择2013—2015年沧州市城镇居民健康体检者作为调查对象，收集其甲状腺检查及实验室甲状腺功能检测数据，对其甲状腺功能异常情况进行统计分析。结果共选择健康体检者3218名，甲状腺功能异常检出248例，检出率为7．71％，其中甲状腺功能亢进（甲亢）、亚临床甲亢、甲状腺功能减退（甲减）、亚临床甲减的检出率分别为0．81％（26／3218）、0．68％（22／3218）、1．83％（59／3218）、4．38％（141／3218），亚临沧床甲状腺疾病的检出率（5．07％）高于临床甲状腺疾病的检出率（2．64％，Х^2=32．140，P〈0．01）。2013—2015年甲状腺功能异常的检出率分别为2．73％（24／879）、6．54％（71／1086）、12．21％（153／1253），不同年份比较差异有统计学意义（Х^2=69．443，P〈0．01）。男性甲状腺功能异常检出率为3．20％（49／1532），女性为11．80％（199／1686），女性明显高于男性（Х^2=12．806，P〈0．01）。年龄在40～〈50和≥70岁组甲状腺功能异常检出率居高，分别为10．25％（65／634）和10．40％（31／298）。结论沧州市城镇居民健康人群甲状腺功能异常检出率逐年升高，以亚临床甲减为主，应加强甲状腺疾病的早期诊断和鉴别诊断，及时采取相应干预措施．降低甲状腺及相关疾病的发生。Objective To know about the abnormal condition of thyroid function in healthy population of urban residents in Cangzhou City, to reduce the incidence of thyroid disease to provide a reference. Methods Urban residents participated in a health checkup were selected as respondents in Cangzhou from 2013 to 2015, whose thyroid examination and laboratory test data of thyroid function were collected. Statistical analysis of thyroid dysfunction was performed. Results Totally 3 218 healthy controls with 248 cases of thyroid dysfunction were tested. The detectable rate was 7.71%. The detectable rates of hypothyroidism, subclinical hyperthyroidism, hypothyroidism, and subclinical hypothyroidism were 0.81% （26/3 218）, 0.68% （22/3 218）, 1.83% （59/3 218）, and 4.38% （141/3 218）, respectively. The prevalence of subclinical thyroid disease （5.07%） was higher than that of clinical thyroid disease （2.64%, X2 = 32.140, P 〈 0.01）. The detectable rates of thyroid dysfunction from 2013 to 2015 were 2.73% （24/879）, 6.54% （71/1 086）, and 12.21% （153/1 253）, respectively. The differences among the three were statistically significant （Х^2 = 69.443, P〈 0.01 ）. The detectable rate of male thyroid dysfunction was 3.20% （49/1 532）and female was 11.80% （199/1 686）. The women＇s rate was significantly higher than that of men （X^2 = 12.806, P 〈 0.01）. The majority of patients were in the 40 to under 50 and older than 70 years of age which accounted for 10.25% （65/634） and 10.40% （31/298）, respectively. Conclusions The detectable rate of thyroid dysfunction in healthy population of urban residents in Cangzhou City is increasing year by year, most cases are subclinical hypothyroidism. In the future,early diagnosis and differential diagnosis of thyroid diseases should be strengthened and appropriate intervention measures should be taken to reduce the incidence of thyroid and related diseases.

关 键 词：甲状腺功能 体检 分析 

分 类 号：R581[医药卫生—内分泌]