蒲药灌肠液辅助血府逐瘀胶囊综合治疗气滞血瘀型慢性盆腔炎的临床试验  

Clinical Study on the Qi Stagnation and Blood Stasis Type of Chronic Pelvic Inflammation Treat by Xuefuzhuyu Capsules Plus Puyao Rectal Solution

作　　者：王慧丽[1] 李燕[1] 郑丽娜[1] 王春艳[1] 姜海英[2] 杨丽君[3] 

机构地区：[1]唐山市妇幼保健院药剂科,河北唐山063000 [2]唐山市妇幼保健院妇科,河北唐山063000 [3]唐山市妇幼保健院中医科,河北唐山063000

出　　处：《中国现代应用药学》2017年第9期1322-1325,共4页Chinese Journal of Modern Applied Pharmacy

摘　　要：目的研究蒲药灌肠液辅助血府逐瘀胶囊综合治疗气滞血瘀型慢性盆腔炎的临床疗效,为其临床应用提供科学依据。方法气滞血瘀型慢性盆腔炎患者122例,随机分为对照组和试验组。对照组口服血府逐瘀胶囊,试验组口服血府逐瘀胶囊同时辅助蒲药灌肠液治疗,2个疗程后比较2组治疗效果。结果试验组愈显率为69.4%,总有效率为93.6%;对照组愈显率为43.3%,总有效率为81.6%;两组比较差异有统计学意义(P<0.05)。试验组在改善中医证候和局部体征方面,降低高切全血黏度、血浆黏度和红细胞积压方面优于对照组,差异有统计学意义(P<0.05)。结论蒲药灌肠液辅助血府逐瘀胶囊综合治疗气滞血瘀型慢性盆腔炎,可以明显提高治疗效果,且能改善患者血液流变性,值得临床推广。OBJECTIVE To corroborate the therapeutic effects for Qi stagnation and blood stasis type of chronic pelvic inflammation under the treatment of Xuefuzhuyu capsules plus Puyao rectal solution, and provide scientific basis for its clinical application. METHODS The 122 patients of Qi stagnation and blood stasis type of chronic pelvic inflammation were randomly assigned into two groups named control and experimental group, respectively. The control group were orally administrated with Xuefuzhuyu capsules only. The experimental group were treated with Xuefuzhuyu capsules together with Puyao rectal solution. The therapeutic effects between groups were compared at the end of two courses of treatment. RESULTS In the experimental group, the remarkably effective rate was 69.4% and the total efficiency was 93.6%; in the control group, the remarkably effective rate was 43.3% and the total efficiency was 81.6%, the differences were statistically significant with P0.05. The experimental group were better than the control group in the improvement of TCM syndromes and the local signs, in reducing the high shear whole blood viscosity, plasma viscosity and hematocrit, the differences were statistically significant with P0.05. CONCLUSION The therapeutic effect for Qi stagnation and blood stasis type of chronic pelvic inflammation under the treatment of Xuefuzhuyu capsules can be significantly enhanced with Puyao rectal solution. The drug combination can strengthen the effect, improve the blood rheology, is worth further promotion.

关 键 词：慢性盆腔炎 气滞血瘀 血府逐瘀胶囊 蒲药灌肠液 

分 类 号：R969.4[医药卫生—药理学]