7098例泌尿生殖道标本支原体感染状况及药敏结果分析  

Urogenital tract Mycoplasma infection status and drug sensitivity of 7 098 cases

作　　者：宁兴旺[1] 钱纯[1] 匡敏[1] 朱惠斌[1] 谢小兵[1] 

机构地区：[1]湖南中医药大学第一附属医院医学检验中心,湖南长沙410007

出　　处：《中国热带医学》2017年第10期1041-1043,共3页China Tropical Medicine

摘　　要：目的了解近年来长沙地区泌尿生殖道支原体感染状况及常用药物敏感性的特征,为临床诊疗及合理用药提供依据。方法采集2016年6月—2017年2月门诊患者的泌尿生殖道标本,进行解脲脲原体(Uu)和人型支原体(Mh)培养及药敏试验,分析培养及药敏结果。结果共收集7 098例泌尿生殖道支原体标本,共检出阳性标本2 123例,总阳性率29.9%。女性患者感染率32.9%,男性患者感染率18.5%,不同性别患者感染率差异有统计学意义(P<0.05)。不同年龄组间感染率差异有统计学意义(P<0.05),48~57岁组感染率最高,≥68岁组感染率最低。不同型别以Uu单纯感染为主,占82.0%,其次是Uu+Mh混合感染,占14.4%。不同感染型别对常用药物存在不同程度的耐药,Uu+Mh混合感染的耐药率最高。结论近年来长沙地区泌尿生殖道支原体以Uu单纯感染为主,美满霉素、强力霉素和交沙霉素对不同型别支原体感染有较好的敏感性。Objective To investigate the conditions of urogenital tract Mycoplasma infection and drug sensitivity inrecent years in Changsha region, so as to provide the evidence for the rational use of antimicrobial drugs in clinics.Methods From June 2016 to February 2017, the urogenital tract specimens of outpatients were collected to cultivate Ureaplasma urealytium（Uu） and Mycoplasma hominis（Mh）. The positive specimens and results of drug sensitivity tests wereanalyzed. Results Among 7 089 inspected specimens, 2 123 were positive with the rate of 29.9%. The infection rate of thefemales（32.9%） was significantly higher than that of the males（18.5%）, and there was a significant difference between thedifferent genders（P0.05）. There was a significant difference among different age groups in Mycoplasma infection rates（P0.05）, and the patients between 48 and 57 years old presented the highest infection rate, and the individuals older than 68 yearspresented the lowest. The single infection of Uu was the main form（82.0%） in the infected specimens, and the multi-infectionsof Uu and Mh amounted for 14.4%. The patients with different infection types displayed different degrees of resistance tocommonly used drugs. The commonly used dug sensitivity tests showed that the drug resistance rate of mixed infections of Uuand Mh was significantly higher than that of Uu or Mh infection. Conclusions The single infection of Uu is the main form ofurogenital tract Mycoplasma infection in Changsha region in recent years. The infection rate of the females is significantlyhigher than that of the males. Minocycline, doxycycline and josamycine have better sensitivity in treatment of different kinds of Mycoplasma infection.

关 键 词：泌尿生殖道 支原体 感染 药物敏感性 

分 类 号：R375[医药卫生—病原生物学]