侵袭性肺部真菌感染的中医证素特点研究  

Study on the characteristics of TCM syndrome factors of invasive pulmonary fungal infection

作　　者：李昕原[1] 梁腾霄[1,2] 王兰[1,2] 

机构地区：[1]北京中医药大学东直门医院急诊科,100700 [2]北京中医药大学东直门医院热病研究所,100700

出　　处：《环球中医药》2017年第10期1174-1177,共4页Global Traditional Chinese Medicine

基　　金：国家中医临床研究基地业务建设科研专项(JDZX2015301;JDZX2015304);北京中医药大学薪火传承研究课题:北京中医药薪火传承"3+3"工程

摘　　要：目的总结侵袭性肺部真菌感染患者中医证素特点。方法收集北京中医药大学东直门医院2012年1月1日至2013年12月31日符合侵袭性肺部真菌感染临床诊断住院患者进行回顾性调查,选取其中病例记录全面详实、能完整体现患者整体状态、符合纳入标准者共175例,统计分析患者侵袭性肺部真菌感染前后及感染不同真菌菌属后证素变化,总结中医证素特点。结果(1)侵袭性肺部真菌感染病人病位证素涉及广泛,主要在肺、脾、胃、肾等。(2)病性虚实夹杂,以虚为主,证素在痰、湿、热、气虚、阳虚、血虚、阴虚、血瘀等。(3)白假丝酵母菌与非白假丝酵母菌在病位证素脾、胃、肾及病性证素湿、气虚、阳虚、血虚、阴虚、血瘀上均存在统计学差异(P<0.05)。结论侵袭性肺部真菌感染患者有其中医证素特点,值得进一步挖掘,同时也应加强对不同真菌菌属相应特点的研究,更好的服务临床。Objective To summarize characteristics of TCM syndrome factors of patients with invasive pulmonary fungal infections. Methods Retrospective study of patients with invasive pulmonary fungal infection were selected from January 1, 2012 to December 31, 2013 in Dongzhimen hospital of Beijing University of Chinese Medicine. 175 cases of complete case notes were accordance with the inclusive criteria. The changes of TCM syndrome factors at before and after infection were analyzed,and the characteristics of TCM syndrome elements was summarized. Results （1） Disease location of syndrome elements in patients with invasive pulmonary fungal infections were involved in a wide range, mainly in the lung, spleen, stomach, kidney, etc. （2） Nature of disease was intermingled deficiency and excess, most cases were deficiency, syndrome element including： phlegm, damp, heat, qi-deficiency, yang-dificiency, blood-dificiency, yin-deficiency, blood stasis, etc. （3） Location of TCM syndrome factor was sleen, stomach, kidney, and nature of TCM syndrome factor was damp, qi-deficiency, yang-deficieny, blood-de-ficiency, yin-deficiency, blood-stasis, etc. There were statistical difference between candida albicans infection and non-candida （P〈0. 05）. Conclusion Invasive pulmonary fungal infection patients have the characteristics of TCM syndrome factors, it is worthy of further investigation, and should strengthen the research on characteristics of different fungi, to provide better service to the clinic.

关 键 词：肺部感染 真菌 中医证候 白假丝酵母菌 

分 类 号：R563.1[医药卫生—呼吸系统]