小儿腹泻大便培养结果与血清中心肌损伤标志物的关系  

Relationship between stool culture results and markers of serum central muscle injury in children with diarrhea

作　　者：王艳[1] 郑义雪 陈丽珠[1] 陈杰奎[1] 王文琼[2] 

机构地区：[1]三亚市中医院儿科,海南三亚572000 [2]荆州市中心医院,湖北荆州434000

出　　处：《中国卫生检验杂志》2017年第19期2789-2791,共3页Chinese Journal of Health Laboratory Technology

摘　　要：目的探讨小儿腹泻患者大便培养结果与心肌损伤标志物水平的关系。方法收集2012年9月-2016年9月在本院就诊的腹泻患儿650例,进行粪便培养,检测患儿血清中心肌损伤标志物肌钙蛋白I(c Tn I)和肌红蛋白(Mb)、肌酸肌酶同工酶(CK-MB),探讨大便培养结果与心肌损伤标志物水平的关系。结果腹泻组患儿CK-MB正常320例、异常330例,Mb正常380例、异常270例,c Tn I正常327例、异常323例,与对照组比较,异常率明显升高,差异有统计学意义(P<0.05)。轮状病毒腹泻组患儿CK-MB正常59例、异常191例,Mb正常100例、异常150例,c Tn I正常72例、异常178例,与细菌阳性组和阴性组对比,异常率均升高,差异有统计学意义(P<0.05)。结论轮状病毒腹泻患儿血清中心肌损伤标志物明显异常,而且患儿电解质紊乱情况更明显,值得临床重点关注。Objective To investigate the relationship between the results of stool culture and the markers of myocardial injury in children with diarrhea. Methods 650 cases of infantile diarrhea from September 2012 to September 2016 in our hospital were selected,fecal were cultured and cardiac troponin I（ c Tn I） myoglobin（ Mb） were tested,creatine kinase isoenzyme（ CK-MB） were used to explore the relationship between the results of stool culture and myocardial injury markers. Results In the diarrhea group,there were 320 cases of nomal CK-MB and 330 cases of abnormal CK-MB,380 cases of normal Mb and 270 cases of abnormal Mb,327 cases of normal c Tn I and 323 cases of abnormal c Tn I; compared with the control group,the abnormal rate significantly increased,and the differences were statistically significant（ P〈0. 05）. In the rotavirus diarrhea group,there were 59 cases of nomal CK-MB and 191 cases of abnormal CK-MB,100 cases of normal Mb and 150 cases of abnormal Mb,72 cases of normal c Tn I and 178 cases of abnormal c Tn I; compared with the positive bacterria group and the negative bacterria group,the abnormal rate significantly increased,and the differences were statistically significant（ P〈0. 05）. Conclusion The serum markers of muscle damage in children with rotavirus diarrhea are obviously abnormal,and the electrolyte disorders in children are more obvious,which is worthy of clinical attention.

关 键 词：血清肌钙蛋白Ⅰ 肌红蛋白 大便培养 心肌炎 

分 类 号：R446.1[医药卫生—诊断学]