PET/CT下合并肺不张非小细胞肺癌的治疗结果和预后分析  

Analysis of Effect and Prognosis of PET/CT in Treatment of Pulmonary Atelectasis Non-small Cell Lung Cancer

作　　者：李广贺[1] 

机构地区：[1]枣庄市立医院新城分院全科医学科,山东枣庄277800

出　　处：《世界复合医学》2017年第3期39-41,共3页World Journal of Complex Medicine

摘　　要：目的分析比较PET/CT扫描检查指导下放射性治疗合并肺不张的非小细胞肺癌的治疗效果,分析探讨影响预后的因素。方法回顾分析该院放疗科2014年9月—2015年8月收治的伴有不同程度肺不张的非小细胞肺癌患者54例,根据治疗定位方法不同分为两组,PET-CT定位系统下29例作为观察组,CT定位系统下25例作为对照组,观察两组患者12个月生存率及肿瘤靶病灶疗效,并对可能影响预后的因素进行单因素分析。结果放疗后12个月生存率观察组为72.41%,对照组为56.00%,观察组显著高于对照组,差异有统计学意义(χ~2=3.204,P<0.05);经治疗,观察组总有效率为85.71%,对照组总有效率为50.00%,观察组治疗效果优于对照组,差异有统计学意义(χ~2=3.974,P<0.05);预后影响因素Logistic回归分析结果显示临床分期、肺不张范围、是否复张和治疗前血红蛋白含量是影响肺不张合并肺不张的非小细胞肺癌预后的独立因素。结论 PETCT扫描检查对放疗靶区的精确定位进行放射性治疗非小细胞肺癌合并肺不张具有重要的临床意义。充分考虑影响预后的因素,严格把握适应证,以获得最佳的治疗效果。Objective To compare and analyze the effect of PET/CT in treatment of pulmonary atelectasis non-small cell lung cancer and study the influence factors of prognosis. Methods 54 cases of patients with different degrees of pulmonary atelectasis non-small cell lung cancers admitted and treated in our hospital from September 2014 to August 2015 were selected and divided into two groups according to the treatment methods, the observation group were 29 cases under the PET-CT orientation system, and the control group were 25 cases under the CT orientation system, and the 12-month survival rate and tumor target lesion curative effect of the two groups were observed and the potential influence factors were given the single-factor analysis. Results After the radiotherapy, the 12-month survival rate in the observation group was higher than that in the control group,（72.41% vs 56.00%）,（χ^2=3.204,P〈0.05）, and the difference was obvious, after treatment, the total effective rate in the observation group was better than that in the control group,（85.71% vs 50.00%）,（χ^2=3.974,P〈0.05）, and the difference was obvious, and the Logistic regression analysis results showed that the clinical stage, pulmonary atelectasis range, pulmonary recruitment or not and hemoglobin content before treatment were the independent influence factors of prognosis of pulmonary atelectasis non-small cell lung cancer. Conclusion The PET-CT scan examination for accurate orientation of radiotherapy target region in the radiotherapy of pulmonary atelectasis non-small cell lung cancer is of important clinical significance, and we should fully consider the influence factors of prognosis and strictly master the indications in order to obtain the best treatment effect.

关 键 词：PET/CT 肺不张 非小细胞肺癌 治疗效果 预后分析 

分 类 号：R4[医药卫生—临床医学]