维生素D缺乏与儿童哮喘的关系  

Relationship of vitamin D deficiency with asthma in children

作　　者：陈江[1] 任翼[1] 何娜[1] 石霖[1] CHEN Jiang REN Yi HE Na SHI Lin(Department of Pediatrics, the Maternal and Child Health Hospital of Haikou, Haikou 570102, China)

机构地区：[1]海南省海口市妇幼保健院儿科,海口市570102

出　　处：《广西医学》2017年第10期1471-1473,共3页Guangxi Medical Journal

基　　金：国家自然科学基金(30960411);海南省科技项目([2012]36)

摘　　要：目的探讨维生素D缺乏与儿童哮喘的关系。方法选取78例哮喘患儿为观察组,78例健康儿童为对照组,比较两组间以及不同哮喘严重程度和控制情况患儿间的血清维生素D水平,分析儿童哮喘发病的影响因素。结果观察组血清维生素D水平低于对照组(P<0.05),但不同哮喘严重程度及控制情况患儿的血清维生素D水平比较,差异均无统计学意义(均P>0.05)。多元logistic回归分析结果显示,维生素D缺乏是儿童哮喘发病的独立危险因素(P<0.05)。结论维生素D的缺乏可增加儿童哮喘的患病风险。Objective To investigate the relationship of vitamin D deficiency with asthma in children. Methods Seventy-eight children with asthma were enrolled as observation group,and 78 healthy children as control group. Serum levels of vitamin D were compared between the two groups ,or among children with various severities of asthma or with various control situations of asthma. The factors influencing asthma attack in children were analyzed. Results The level of serum vitamin D in the observation group was lower than that in the control group （P 〈 0. 05 ） ,but there was no statistically significant difference in the serum level of setum vitamin D among children with various severities of asthma or with various control situations of asthma（ all P 〉 0.05 ）. The results of multivariate logistic regression analysis revealed that vitamin D deficiency was an independent risk factor for asthma attack in children （ P 〈 0.05 ）. Conclusion Vitamin D deficiency might increase the risk of asthma in children.

关 键 词：哮喘 维生素D缺乏 儿童 危险因素 

分 类 号：R725.6[医药卫生—儿科]