HPLC法同时测定瓜蒌薤白片中3种成分的含量  

Simultaneous Determination of Three components in Gualou Xiebai Tablet by HPLC

作　　者：陈素慧[1] 林向前[2] 陈丹[3] 

机构地区：[1]漳州卫生职业学院,福建漳州363000 [2]漳州市中医院,福建漳州363000 [3]福建中医药大学,福州350003

出　　处：《江西中医药大学学报》2017年第5期58-61,共4页Journal of Jiangxi University of Chinese Medicine

基　　金：福建省教育厅青年基金项目(JA15852);漳州科技局自然科学基金项目(ZZ2016J39);漳州卫生职业学院青年人才培育计划项目

摘　　要：目的:建立瓜蒌薤白片中代表性成分丹酚酸B、柚皮苷、盐酸小檗碱的含量测定方法。方法:采用高效液相色谱法测定瓜蒌薤白片中丹酚酸B、柚皮苷、盐酸小檗碱的含量。结果:建立同时测定中药复方制剂瓜蒌薤白片中表性成分丹酚酸B、柚皮苷、盐酸小檗碱含量的方法。每片中丹酚酸B的含量不低于2.1mg、柚皮苷的含量不低于2.1mg、盐酸小檗碱含量不低于1.2mg。结论:本实验首次建立的HPLC法同时测定中药复方制剂瓜蒌薤白片中丹酚酸B、柚皮苷、盐酸小檗碱含量的定量分析方法,该法简便准确,可用于瓜蒌薤白片的质量控制。Objective： Establish the method of etermination of contents of salvianlic acid B,naringin,berberine hydrochloride in Gualou Xiebai Tablet. Methods： Using HPLC to determine contents of salvinolic acid B,naringin,berberine hydrochloride in Gualou Xiebai Tablet. Result： Establishment of Traditional Chinese Medicine Gualou Xiebai Tablet component Salvianlic acid B,naringin,berberine hydrochloride method for simultaneous determination. Salvianlic acid B content per tablet is not less than 2. 1mg,naringin content of not less than 2. 1mg,berberine hydrochloride not less than 1. 2mg. Conclusiong： The first experiment established HPLC method for simultaneous determination of the contents Salvianlic acid B,naringin,berberine hydrochloride of in Traditional Chinese Medicine Gualou Xiebai Tablet. This method simple and accurate and can be used for quality control Chest tablets.

关 键 词：HPLC 丹酚酸B 柚皮苷 盐酸小檗碱 含量 

分 类 号：R284.1[医药卫生—中药学]