双氯芬酸钠利多卡因合用止痛剂治疗疼痛的疗效研究  

Study of Diclofenac sodium and Lidocaine combined with analgesics for treatment of pain

作　　者：任鹏涛[1] 张苑[2] 阎庆辉[1] 张国建[1] 郝英豪[1] 

机构地区：[1]河北医科大学第二医院肛肠外科,河北石家庄050000 [2]河北医科大学第二医院心电图室,河北石家庄050000

出　　处：《中国现代医学杂志》2017年第23期91-94,共4页China Journal of Modern Medicine

摘　　要：目的探讨双氯芬酸钠利多卡因合用止痛剂治疗疼痛的临床有效性。方法以该院肛肠科接受手术患者148例,分为观察组和对照组。观察组采用双氯芬酸钠利多卡因联合止痛剂止痛,对照组使用止痛剂。观察两组患者术后镇痛情况并统计两组并发症情况。结果不同时间VAS评分比较,差异有统计学意义(P<0.05),两组VAS评分比较,差异有统计学意义(P<0.05),两组VAS评分变化趋势比较,差异有统计学意义(P<0.05)。术后不同时间RASS评分比较,差异有统计学意义(P<0.05),两组RASS评分比较,差异有统计学意义(P<0.05),两组的RASS评分变化趋势比较,差异有统计学意义(P<0.05)。观察组并发症发生率高于对照组。结论双氯芬酸钠利多卡因与长效止痛剂合用能减轻肛肠病术后疼痛,并降低并发症率,值得在临床上进一步推广。Objective To investigate clinical efficacy of Diclofenac sodium and Lidocaine combined with analgesics in the treatment of pain. Methods In our hospital 148 cases undergoing anorectal surgery were divided into observation group and control group. The observation group was treated with Diclofenac sodium and Lidocaine combined with analgesics, the control group only used analgesics. The postoperative analgesia was observed and the occurrences of complications were analyzed in the two groups. Results The scores of VAS were different at different time points（F = 11.983, P = 0.000）. The VAS scores were different between the observation group and the control group（F = 25.376, P = 0.000）, the observation group was different from the control group in the VAS score change trend（F = 10.307, P = 0.000）. There were significant differences in the SS scores at different time points（F = 7.016, P = 0.001）. The SS scores of the observation group and the control group were significantly different（F = 14.375, P = 0.000）, the change trend of the SS scores was different between the observation group and the control group（F = 6.309, P = 0.003）. The incidences of complications in the observation group were significantly higher than those in the control group. Conclusions Combination of Diclofenac sodium and Lidocaine with long-acting analgesics can significantly reduce postoperative anorectal pain and the rate of complications, is worthy of further promotion in clinical practice.

关 键 词：双氯芬酸钠利多卡因 长效止痛剂 肛肠病 术后疼痛 

分 类 号：R441.1[医药卫生—诊断学]