植物组蛋白去乙酰化酶的特性及功能  

Characteristic and Function of Histone Deacetylases in Plants

作　　者：韩召奋[1] 王秋苹 罗鑫娟[1] 

机构地区：[1]西北农林科技大学生命学院,陕西杨凌712100

出　　处：《中国生物化学与分子生物学报》2017年第10期1008-1013,共6页Chinese Journal of Biochemistry and Molecular Biology

基　　金：国家自然科学基金项目(No.31400233)资助~~

摘　　要：真核生物染色质修饰是基因表达调控中的一个重要部分,组蛋白乙酰化修饰是基因转录调控的关键机制,与基因表达的活跃与沉默密切相关。组蛋白乙酰化修饰已成为表观遗传学的重要组成部分,受到研究者的普遍重视。本文从植物组蛋白去乙酰化酶(histone deacetylase,HDACs)的分类开始,综述植物中HDACs家族成员的结构特点、组织表达的多样性与复杂性,重点阐述其对发育的调控、逆境胁迫的响应。对了解基因的调控机制,丰富表观遗传学内容,并最终应用于植物育种及农业生产具有重要意义。Eukaryotes chromatin modification is an important factor of gene expression regulation in epigenetics. Histone acetylation plays a key role in mechanism of gene transcription, which affects gene activation or gene silencing. Histone acetylation modification has become an important part of epigenetics and there have been many researches focusing on this field. This paper reviews recent findings on HDACs, their classification, structural characteristics and variety and complexity of tissue expression, especially their roles in regulation of development and responses to stress in plants. It is useful to know the mechanism of gene regulation and enrich the details of epigenetics, which would be great value applied to breeding practices in agriculture eventually.

关 键 词：植物 组蛋白去乙酰化酶(HDACs) 组蛋白修饰 发育 抗逆 

分 类 号：Q37[生物学—遗传学]