川厚朴及其炮制品中单萜和倍半萜类成分研究  

The study of monoterpenes and sesquiterpenes in Magnolia officinalis and its processed products

作　　者：夏新中[1] 肖静[2] 夏庭君[3] 

机构地区：[1]长江大学医学院,湖北荆州434023 [2]湖北省孝感市中心医院,湖北孝感432100 [3]湖北生态工程职业技术学院,湖北武汉430065

出　　处：《时珍国医国药》2017年第9期2109-2111,共3页Lishizhen Medicine and Materia Medica Research

基　　金：湖北省卫计委医药院校专项项目(No.WJ2016-Y-03)

摘　　要：目的分析厚朴炮制前后的挥发油化学成分,为其质量评价提供科学依据。方法采用水蒸气蒸馏(SD)法提取挥发油化学成分,利用气相色谱-质谱联用技术分离鉴定化学成分,采用峰面积归一化法测定相对质量分数。结果从厚朴生品及炮制品中分别鉴定了55种和49种成分,其中相对质量分数在0.1%以上的分别为36种和39种。结论采用水蒸气蒸馏法提取厚朴炮制前后的挥发油,其化学成分基本相同,在质量分数上有所变化,炮制后部分成分的含量有所降低或增加,同时新增加或消失了部分成分。Objective To analyze the volatile terpenes before and after processing the chemical components of Magnolia officinalis,and provide the scientific basis for quality evaluation. Methods The volatile oil was extracted by steam distillation（ SD）.The chemical constituents were separated and identified by gas chromatography-mass spectrometry（ GC-MS）. The relative mass fraction was determined by peak area normalization method. Results 55 and 49 compounds were identified in Magnolia products and processed products. The relative content of 36 and 39 compounds were 0. 1% or more. Conclusion The chemical constituents of the volatile terpenes were the same before and after processing the chemical components of Magnolia officinalis by steam distillation method. The change in the quality scores after processing,the content of some of the components is reduced or increased,and some components are added or disappeared.

关 键 词：厚朴 水蒸气蒸馏法 单萜 倍半萜 

分 类 号：R284.1[医药卫生—中药学]