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作 者:王海涛 方丽丽[1] 谭占国[1] 刘晓璟[1] 谷永娟 杜鹃[1]
机构地区:[1]漯河市中心医院/漯河医专第一附属医院,漯河462000
出 处:《上海针灸杂志》2017年第10期1168-1172,共5页Shanghai Journal of Acupuncture and Moxibustion
基 金:河南省教育厅科学技术研究重点项目(15A360013)
摘 要:目的观察醒脑开窍针法对脑梗死急性期患者认知功能、运动功能及神经功能的影响。方法收集脑梗死急性期患者64例,随机分为试验组和对照组,每组32例。对照组予以依达拉奉联合纤溶酶注射液进行治疗,依达拉奉30 mg,纤溶酶200单位+0.9%氯化钠注射液500 m L静脉滴注,每日1次。试验组在对照组的基础上予以醒脑开窍针法治疗,每日1次,每星期5次。两组均连续治疗2星期。治疗结束后对比两组临床疗效、认知功能、运动功能、神经功能、血清CRP和NO水平以及不良反应发生情况。结果治疗后,两组CSS评分水平降低,LOTCA评分、BI评分及上下肢运动功能评分升高,差异具有统计学意义(P<0.05);试验组临床总有效率高于对照组(P<0.05),试验组CSS水平较低,LOTCA评分、BI评分以及上下肢运动功能评分较高,差异具有统计学意义(P<0.05),治疗后1 d、3 d、7 d以及14 d血清CRP和NO水平较低,差异具有统计学意义(P<0.05)。两组患者不良反应发生率无明显差异(P>0.05)。结论醒脑开窍针法治疗脑梗死急性期患者的临床疗效显著,能够改善认知功能、运动功能及神经功能,安全性较高。Objective To observe the effect of Xing Nao Kai Qiao(awakening brain and opening orifice) needling method on the cognitive and motor function of patients in acute stage of cerebral infarction. Method Sixty-four patients in acute stage of cerebra infarction were recruited and randomized into a trial group and a control group, 32 cases in each group. The control group was intervened by Edaravone 30 mg plus Fibrinogenase injection 200 U mixed in 500 m L 0.9% Na Cl via intravenous drip, once a day. The trial group was by Xing Nao Kai Qiao needling method in addition to the intervention given to the control group, once a day, 5 times a week. The two groups were both given 2-week successive treatment. At the end of the intervention, clinical efficacy, cognitive function, motor function, nervous function, serum C-reactive protein and NO levels, and adverse reactions of the two groups were compared. Result After the treatment, the Chinese Stroke Scale(CSS) score dropped significantly, Loewenstein Occupational Therapy Cognitive Assessment(LOTCA) score, Barthel Index(BI) score and motor function score of both upper and lower limbs increased significantly in both groups(P〈0.05); the total effective rate of the trial group was significantly higher than that of the control group(P〈0.05); the CSS score was lower, and LOTCA score, BI score, and motor function scores of both upper and lower limbs were higher in the trial group compared with those in the control group, and the differences were statistically significant(P〈0.05); on the 1st, 3rd, 7th and 14 th day after the intervention, the serum CRP and NO levels were significantly lower in the trial group compared with those in the control group(P〈0.05). There was no significant difference in comparing the adverse reaction incidence between the two groups(P〈0.05). Conclusion Xing Nao Kai Qiao needling method can produce a significant efficacy in treating patients in acute stage of cerebral infarction, and it can improve the cognitive
关 键 词:针刺 醒脑开窍针法 脑梗死 NIHSS评分 LOTCA评分 BARTHEL指数 CSS评分 针药并用
分 类 号:R246.6[医药卫生—针灸推拿学]
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