血栓弹力图在重症中暑患者中的应用研究  

Study on the application of MR in patients with severe heat stroke

作　　者：吴长江[1] 隋明亮 徐云峰[1] 黎宁君[1] 

机构地区：[1]上海交通大学医学院附属苏州九龙医院重症医学科,江苏苏州215028

出　　处：《吉林医学》2017年第10期1821-1824,共4页Jilin Medical Journal

摘　　要：目的:探讨重症中暑患者入院早期血栓弹力图指标与预后的关系。方法:回顾分析30例重症中暑患者的临床资料,按照患者预后分为存活组(38例)和死亡组(4例)。收集患者入院1,2,3,5,7天内血栓弹力图指标的值,比较两组患者R值,K值(凝血形成时间),α值(血形成速率),MA(最大反映幅度)的差异。结果:在入院后第3天起死亡组R值延长、MA值缩短,入院后第5天起K值延长、α值降低。与生存组比较,两组相应时相点数值差异有统计学意义(P<0.05)。结论:TEG能够准确反映重症中暑患者凝血/纤溶过程中不同成分的功能,而MA值与血小板计数值同步并持续降低,则提示患者预后不良。Objective To discuss the relationship between early thrombelastography parameters at admission in patients with severe heatstroke and their outcome. Method The data from 30 patients with severe heatstroke were retrospectively analyzed. The patients were divided into survival group（ n = 38） and non-survival group（ n = 4）. The incipient values of thrombelastography parameters indexes with in 1,2,3,5,7 d after admission were collected,and R time（ reaction time）,early clot initiation（ K）,initial kinetic of clot development（ angleα） and clot strength（ maximum amplitude,MA） were compared between two groups to assess the statistically significant indexes for the analysis of the relationship between thrombelastography parameters. Results Compared with those in survivalgroup,R time and K time were significantly prolonged,angle α and MA were significantly reduced in non-survivalgroup（ P〈 0. 05）. Conclusion Early reduced MA and PLT count are associated with increased risk of death,and it can predict a poor outcome in patients with severe heatstroke.

关 键 词：中暑 重症 凝血功能 血小板 预后 

分 类 号：R594.12[医药卫生—内科学]