蛹虫草口服液提取工艺的研究  

Study on the Extraction Technology of Yongchongcao Oral Liquid (蛹虫草口服液)

作　　者：崔思娇[1] 杨光照[2] 于士龙[1] 薛强[1] 汪宇[1] CUI Si-jiao YANG Guang-zhao YU Shi-long QUE Qiang WANG Yu(Chinese People＇s Liberation Army No. 463 Hospital, Shenyang Liaoning 110042, China The General Hospital of Shenyang Military Command, Shenyang Lianning 110016, China)

机构地区：[1]中国人民解放军第四六三医院,辽宁沈阳110042 [2]中国人民解放军沈阳军区总医院,辽宁沈阳110016

出　　处：《中医药导报》2017年第19期53-54,60,共3页Guiding Journal of Traditional Chinese Medicine and Pharmacy

基　　金：军队疗医机构制剂标准提高项目:中药口服液体制剂提取精制工艺改进与质量控制体系研究(13ZJZ01-5)

摘　　要：目的:筛选蛹虫草口服液总多糖的最佳提取工艺。方法:采用正交设计试验考察提取温度、提取时间、料液比和提取次数四因素对蛹虫草口服液多糖提取率的影响。结果:最佳提取工艺条件为:提取温度为100℃、提取时间为2 h、料液比为1:10(g/mL)、提取次数为3次。在最佳提取工艺条件下,蛹虫草口服液多糖的提取率为2.781%。结论:优选的工艺稳定可行,可为蛹虫草口服液的生产提供参考。Objective： To optimize the extraction technology of polysaccharide in Yongchongcao Oral Liquid. Methods： The study applied the orthogonal test to discusse the influences of temperature, time, solid-liquid ratio and extraction times on extraction yield of polysaccharide in Yongchongcao oral liquid. Results： The optimal extraction condition was extraction temperature of 100℃, extraction time of 2 h, solid-liquid ratio of 1：10 （g/mL） and extracted three times. Under the optimal extraction condition, the extracting rate of polysaccharide in Yongchongcao oral liquid is 2.781%. Conclusion： The optimal extraction technique with better repeatability is stable, which can provide the reference for the production of Yongchongcao Oral Liquid.

关 键 词：蛹虫草口服液 多糖 提取工艺 正交试验 

分 类 号：R284.1[医药卫生—中药学]