某院623例药品不良反应报告分析  

Analysis on 623 case's reports with adverse drug reaction in a hospital of PLA

作　　者：黄月莹[1] 高欣涛[1] 刘弘[1] 

机构地区：[1]解放军152医院药学部,河南平顶山467099

出　　处：《实用医药杂志》2017年第10期926-929,共4页Practical Journal of Medicine & Pharmacy

摘　　要：目的了解某院药品不良反应(ADR)发生的一般规律及特点,为临床合理用药提供参考。方法采用回顾性分析方法,对某院2011-01-01—2015-12-31收集的623例填报完整和有分析评价的ADR报告进行分析。结果 ADR发生的男、女比例为0.99∶1;静脉滴注引发ADR的比例最高(88.43%);涉及药品种类以抗微生物药最多(39.97%);ADR累及器官或系统最多的是皮肤及其附件(44.66%)、全身性损害(21.96%)等。结论医院应积极、规范地开展ADR监测和上报工作,提高患者的用药安全;药学部门要加大ADR知识的培训,提高医护人员的重视度和积极性。Objective To investigate the feature and in authorJs hospital so as to provide a reference for rational regularity of adverse drug reactions （ADRs） occurred medication in clinic. Methods All the 623 cases of ADRs collected in the hospital from January 1,2011 to December 31,2015 which were reported completely and had obtained analysis evaluation were analyzed retrospectively. Results Among the 623 ADRs cases,the male to female was 0.99：l,the highest percentage belonged to intravenous drip was 88.43%. The antimicrobial drug was the most drug varieties involved （39.37%）. The most common involved organs/systems of ADRs were skin and appendages disorders （44.66%）,followed by systemic lesions （21.96%）. Conclusion The monitoring and reporting ADRs should be carried on positively and normatively in hospital so that to improve the security of using drugs. Pharmacy department should reinforce the training of ADRs knowledge to improve the attention and motivation of the medical staff.

关 键 词：药品不良反应 回顾性分析 监测 

分 类 号：R97[医药卫生—药品]