五加皮中草药活性成分紫丁香苷提取工艺研究  

Optimization of Extracting Process for the Syringoside in Cortex Acanthopanacis

作　　者：王秀皊 刘玉[1] 曹乐 薛洪宝[1] 梁丽丽[1] Wang XiuLing Liu Yu Cao Le Xue Hongbao Liang Lili(Department of Pharmaceutical Engineering, Bengbu Medical College, Bengbu 233030, Chin)

机构地区：[1]蚌埠医学院制药工程系,安徽蚌埠233030

出　　处：《广东化工》2017年第20期32-33,共2页Guangdong Chemical Industry

基　　金：国家级大学生创新创业项目(201510367004)

摘　　要：目的:建立五加皮中活性成分紫丁香苷的最佳提取工艺。方法:通过溶剂回流、超声提取法以及索氏提取法,分别控制反应时间、液料比、溶剂等单因素实验考察其对五加皮中活性成分提取率的影响。结果:五加皮中草药活性成分最佳提取工艺为:丙酮为溶剂、液料比6︰1、回流6小时提取率最高。结论:该方法简单易行,灵敏可靠,经济适用,重复性好,为五加皮中草药中提取活性成分紫丁香苷的提供了一个简单易行的方法。Objective To establish a determination method of extracting process from cortex acanthopanacis by HPLC. Methods Through altering extraction process conditions by single factor test to investigate the extraction effect of active components in cortex acanthopanacis. Results The optimum process conditions are reflux extraction with acetone, liquid-solid ratio of 6 ： 1, reflux, 6 hours. Conclusion： Methodology examination indicated this optimized process is simple, stable, feasible and reliable, suitable for mass production of the active component syringoside.

关 键 词：五加皮 提取工艺 紫丁香苷 高效液相色谱 

分 类 号：TQ461[化学工程—制药化工]