平均血小板体积检测在评估ST段抬高型心肌梗死合并急性肾损伤风险中的意义  

Significance of mean platelet volume in assessing the risk of acute kidney injury in ST-segment elevation myocardial infarction

作　　者：程慧[1] 蒋薇 李一[1] 韩敏 

机构地区：[1]四川省乐山市中医医院,乐山614000

出　　处：《陕西医学杂志》2017年第10期1477-1478,1486,共3页Shaanxi Medical Journal

摘　　要：目的:探讨平均血小板体积(MPV)在评估ST段抬高型心肌梗死(STEMI)合并急性肾损伤(AKI)风险中的意义。方法:将222例STEMI患者按照入院时MPV水平分为MPV增高组(80例)及MPV正常组(140例),记录两组入院后一般临床资料以及住院期间AKI发生情况,利用Logistic回归方程评价MPV在预测AKI发生中的风险。结果:MPV增高组Killip分级、冠脉梗死支数、血清BNP、Scr、cTnI均高于MPV正常组(P<0.05),而eGFR、LVEF低于MPV正常组(P<0.05);MPV增高组AKI发生率高于MPV正常组(P<0.05);Logistic回归分析亦显示:MPV是STEMI合并AKI的独立危险因素。结论:MPV水平增高可能是STEMI合并AKI的独立危险因素,且有一定的风险预测价值,临床应当密切监测MPV水平的变化,以早期评估患者的预后。Objective：To investigate the significance of MPV in assessing the risk of AKI in STEMI.Methods：222 patients with STEMI were divided into Increased MPV group（n=80）and normal MPV group（n=140）according to MPV on admission.General clinical data of two groups occurrence of AKI during hospitalization were recorded.Results：Killip score,coronary infarction count,serum BNP,Scr and cTnI of increased MPV group were higher than those of normal MPV group,the differences were statistically significant（P0.05）;incidence rate of AKI in increased MPV group was higher than normal group.Logistic regression analysis showed that MPV was independent risk factor of AKI.Conclusion：increased MPV level may be an independent risk factor for AKI,and have some predictive value.Clinical monitoring of MPV should be closely monitored to assess the prognosis of patients at an early stage.

关 键 词：平均血小板体积 ST段抬高型心肌梗塞 急性肾损伤 

分 类 号：R541.611[医药卫生—心血管疾病]