芽孢杆菌aiiA基因抗病研究进展  

Research Progress on aii A Gene in Resistance to Disease from Bacillus Species

作　　者：陈珺君 闵勇[2] 刘晓艳[2] 杨自文[1,2] 

机构地区：[1]武汉大学生命科学学院,430072 [2]湖北省农业科学院/湖北省生物农药工程研究中心

出　　处：《长江蔬菜》2017年第20期36-42,共7页Journal of Changjiang Vegetables

基　　金：湖北省农科院竞争性项目(2015jzxjh04);国家自然科学基金青年基金项目(31500428);湖北省创新中心项目(2016-620-000-001-038);湖北省农科院重大研发成果培育专项(2017CGPY01)

摘　　要：aii A基因编码的Aii A蛋白是一类由芽孢杆菌产生的酰基高丝氨酸内酯酶,能够专一性地水解革兰氏阴性菌分泌的AHLs信号分子,从而破坏依赖群体感应系统的致病机制,减轻病原菌的致病性。综述了aii A基因与Aii A蛋白的研究现状、aii A基因在抗病方面的研究进展及Aii A蛋白在工业发展的应用现状等,以期为aii A基因在更多领域的应用提供理论基础。Aii A protein encoded by aii A gene is a kind of acyl-homoserine lactonase produced by Bacillus species that can exclusively hydrolyse the AHLs signal molecules secreted by gram negative bacteria that destroy pathogenic mechanism which depend on the quorum sensing system and reduce the pathogenicity of the pathogen. The essay comprehensively analyzed the research situations of aii A and Aii A, the current research progress of aii A in disease-resistant and the application status of Aii A protein in industrial development, which can provide aii A gene with theoretical basis on more fields of application.

关 键 词：芽孢杆菌 群体感应 aii A基因 N-酰基高丝氨酸內酯(AHLs) 

分 类 号：Q933[生物学—微生物学]