硫酸氢氯吡格雷与阿司匹林联合治疗不稳定型心绞痛的效果探讨  

Effect of clopidogrel hydrogen sulfate combined with aspirin in the treatment of unstable angina pectoris

作　　者：金洪珍[1] 许丁[1] 张盼[1] 

机构地区：[1]北京市平谷区医院心内科,北京101200

出　　处：《中国生化药物杂志》2017年第10期128-129,共2页Chinese Journal of Biochemical Pharmaceutics

摘　　要：目的对硫酸氢氯吡格雷与阿司匹林联合治疗不稳定型心绞痛的临床效果进行分析和探讨。方法选取北京市平谷区医院2015年7月～2016年9月收治的86例不稳定型心绞痛患者为研究对象,采取随机数表法分为2组,每组43例。观察组接受硫酸氢氯吡格雷与阿司匹林联合治疗;对照组接受阿司匹林单独治疗。比较2组患者临床疗效。结果观察组和对照组患者临床不良反应发生率的比较差异无统计学意义（9.30%vs 6.98%）;但观察组患者临床治疗总有效率明显更高（93.02%vs 76.74%,P〈0.05）。结论硫酸氢氯吡格雷与阿司匹林联合使用治疗不稳定型心绞痛效果显著、安全可靠。Objective To analyze and discuss the clinical efficacy of clopidogrel bisulfate combined with aspirin in the treatment of unstable angina pectoris.Methods 86 cases of unstable angina pectoris treated in my hospital from July 2015 to September 2016 were taken as the research object,randomly divided into two groups,with 43 cases in each group.The observation group received clopidogrel combined with aspirin therapy;The control group received aspirin treatment alone.The clinical efficacy of the two groups was compared.Results There was no significant difference in the incidence of adverse reactions between the observation group and the control group（9.30% vs 6.98%）,but the total effective rate of the clinical observation group was significantly higher（93.02% vs 76.74%,P〈0.05）.Conclusion Clopidogrel hydrogen sulfate combined with aspirin in the treatment of unstable angina pectoris is effective,safe and reliable..

关 键 词：硫酸氢氯吡格雷 阿司匹林 不稳定型心绞痛 

分 类 号：R541.4[医药卫生—心血管疾病]