复方制剂芬吗通治疗妇女围绝经期综合征的临床疗效观察  

Clinical effects observation of compound preparation Femoston on treatment of perimenopausal syndrome in women

作　　者：吴解清 钱艳清[2] 徐敏霞 

机构地区：[1]三门县人民医院妇产科,浙江台州317100 [2]温州市中医院中医妇科,浙江温州325000 [3]三门县人民医院中医妇科,浙江台州317100

出　　处：《中国生化药物杂志》2017年第10期175-176,共2页Chinese Journal of Biochemical Pharmaceutics

摘　　要：目的分析复方制剂芬吗通治疗妇女围绝经期综合征的临床疗效。方法选取三门县人民医院2016年4月～2017年7月收治的60例围绝经期综合征妇女为研究对象,随机分为对照组和实验组各30例。对照组给予戊酸雌二醇片,实验组给予复方制剂芬吗通治疗,1片/天。2组患者治疗时间均为6个月,比较分析实验组与对照组患者临床疗效。结果经过对应的治疗后,实验组中,4例患者无效。对照组中,7例患者无效,10例显效,13例有效。可得,实验组治疗有效率为86.67%,显著高于对照组有效率为76.67%,差异具有统计学意义（P〈0.05）。实验组FSH激素水平为（24.10±15.24）U/L显著优于对照组（42.72±15.56）U/L,差异具有统计学意义（P〈0.05）。2组患者均未出现明显不良反应,发生呕吐、腹痛及乳房疼痛等不良反应概率分别为3.33%和6.67%,差异无统计学意义。结论复方制剂芬吗通治疗妇女围绝经期综合征的临床疗效较为理想,能够显著改善患者激素水平,安全性较高。Objective To study and analyze the clinical efficacy of compound preparation Femoston for the treatment of perimenopausal syndrome in women.Methods 60 women with perimenopausal syndrome from April 2016 to July 2017 were selected and randomly divided into the control group and the experimental group,30 cases for each group.The control group was given estradiol valerate tablets,and the experimental group was treated with compound preparation Femoston,one tablet a day.The treatment time of the two groups was 6 months,and the clinical efficacy of the experimental group and the control group were compared and analyzed.Results After the corresponding treatment,4 patients were ineffective in the experimental group.In the control group,7 patients were ineffective,10 cases were effective,and 13 cases were good effective.The effective rate of the experimental group was 86.67%,which was significantly higher than that（76.67%） of the control group with statistical significance（P〈0.05）.The level of FSH in the experimental group was（24.10±15.24） U/L,which was significantly better than that of the control group（42.72 ±15.56） U/L with statistical significance（P〈0.05）.There were no obvious adverse reactions in the two groups,and the rate of adverse reactions such as vomiting,abdominal pain and breast pain were 3.33% and 6.67%,respectively,and there was no statistical significance.Conclusion The clinical efficacy of compound preparation Femoston for treating perimenopausal syndrome is ideal.Femoston could significantly improve the hormone levels in patients with high safety.

关 键 词：复方制剂芬吗通 围绝经期综合征 妇女 临床疗效 

分 类 号：R711[医药卫生—妇产科学]