自拟清解重剂对术后发热患者体温的影响  

Effects of extreme dose of heat-clearing drugs on the temperature of the patients with postoperative fever

作　　者：王剑平[1] 易璐莹[2] 王浩[3] 吴增安[1] Wang Jianpmg H Luying Wang Hao Wu Zeng＇an(Department of Surgery, Wangling Hospital of China Academy of Chinese Medical Sciences, Beijing 100102, China)

机构地区：[1]中国中医科学院望京医院外一科,北京100102 [2]北京市昌平区中西医结合医院内一科,102208 [3]北京中医药大学基础医学院,100102

出　　处：《国际中医中药杂志》2017年第10期899-901,共3页International Journal of Traditional Chinese Medicine

基　　金：北京市中医药科技项目（JJ2011-96）

摘　　要：目的 观察自拟清解重剂对术后发热患者体温的影响.方法 将符合入选标准的70例术后发热患者采用随机数字表法分为2组,每组35例.观察组口服自拟清解重剂,对照组结合临床表现对症治疗.2组均治疗3 d,随访3 d.观察并比较2组患者服药前后体温变化,药物起效时间及解热时间.结果 治疗后第3天,观察组最高体温[（37.5±0.5）℃比（37.6±0.5）℃、（38.1±0.5）℃、（38.3±0.5）℃,F=20.883]、对照组最高体温[（37.5±0.6）℃比（37.5±0.5）℃、（38.1±0.6）℃、（38.4±0.4）℃,F=25.088]均较同组治疗后第2天、第1天及治疗前下降（P〈0.01）.随访第3天,观察组最高体温[（36.9±0.5）℃比（37.1±0.2）℃、（37.3±0.5）℃,F=7.778]较同组随访第2天、第1天及治疗前下降（P〈0.01）.结论 自拟清解重剂可有效降低术后发热患者的体温,其药物起效时间与解热时间与西医常规疗法相近.Objective To observe the effect of exteme dose of heat-clearing drugs on temperature in the postoperative fever patients.Methods A total of 70 patients with postoperative fever who met the inclusion criteria were randomly divided into the control group （35 patients） and observation group （35 patients）. The observation group was treated with exteme dose of heat-clearing drugs, and the control group was treated with the common dose formula. Both groups were treated for 3 day, and followed up for 3 day. The changing of the temperature before and after treatment, the onset time and time of relieving fever were analyzed.Results Compared with the baseline before the treatment, the 1st day, 2nd after treatment, the highest temperature in observation group at thte 3rd day（37.5 ± 0.5℃vs. 37.6 ± 0.5℃, 38.1 ± 0.5℃,38.3 ± 0.5℃,F=20.883） was significantly lower; the highest body temperature in the control group at the 3rd day （37.5 ± 0.6℃vs. 37.5 ± 0.5℃, 38.1 ± 0.6℃, 38.4 ± 0.4℃,F=25.088） was significantly lower （P〈0.01）. At the 3 day in the follow up period, compared with the baseline before the treatment, the 1st day, 2nd after treatment, the highest body temperature in observation group （36.9 ± 0.5℃vs. 37.1 ± 0.2℃, 37.3 ± 0.5℃,F=7.778） were significantly lower （P〈0.01）.Conclusions The high of heat-clearing drugs treatment for the postoperative fever can effectively lower the temperature, and there is no obvious difference of the onset time and the time of relieving fever between two groups.

关 键 词：发热 手术后并发症 解热药 中药 体温 

分 类 号：R269[医药卫生—中西医结合]