335例住院患者华法林用药分析及抗凝强度评价  

Application analysis and anticoagulation intensity evaluation of warfarin in 335 inpatients

作　　者：李振山[1] 陈文文[1] 党和勤[1] 刘燕琳[1] 

机构地区：[1]泰山医学院附属医院药剂科,山东泰安271000

出　　处：《泰山医学院学报》2017年第10期1108-1110,共3页Journal of Taishan Medical College

摘　　要：目的了解住院患者华法林应用情况,探索影响华法林抗凝强度的因素,促进临床合理用药。方法收集2015年1月—2015年12月份我院应用华法林住院患者信息,统计分析性别、年龄、民族、科室分布、合并慢性疾病等因素对国际标准化值(International Normalised Ratio,INR)定期检测率与出院前INR达标率的影响。结果住院患者INR定期检测率为69.25%,出院前达标率为26.27%,65岁(含65岁),以上患者INR定期检测率及出院前达标率低于65岁以下患者(P<0.05),心内科和呼吸内科患者INR定期检测率及出院前达标率高于其他科室患者(P<0.05),主要适应症患者INR定期检测率及出院前达标率高于其他适应症患者(P<0.05)。结论年龄、科室分布、适应症是影响INR定期检测率及出院前达标率的主要因素。Objective： To explore factors affecting anticoagulation intensity by investigating the application of warfarin in inpatients. Methods： Information of inpatients taking warfarin in our hospital from January to December in 2015 was collected as well as the effect of gender,age,nationality,department and comorbidity on International Normalised Ratio（ INR） monitoring rate and standard-reaching rate was analyzed statistically. Results： INR monitoring rate was 69. 25% and standard-reaching rate was 26. 27%,INR monitoring rate and standard-reaching rate of inpatients over 65 years old were both less than which of inpatients under 65 years old（ P〈0. 05）,INR monitoring rate and standard-reaching rate of inpatients in cardiology department and respiratory department were both more than which of inpatients in other deparments（ P〈0. 05）,INR monitoring rate and standard-reaching rate of inpatients with major indication were both more than which of inpatients with other indications（ P〈0. 05）. Conclusion： Age,department and indication could affect the INR monitoring rate and standard-reaching rate.

关 键 词：华法林 INR定期检测率 出院前INR达标率 抗凝强度 

分 类 号：R969[医药卫生—药理学]