北京地区婴幼儿急性腹泻病例5种腹泻相关病毒感染状况  

Investigation on the infection status of the five diarrhea-related viruses among acute infantile diarrheacases in Beijing

作　　者：吉彦莉[1] 王永全[1] 杨青俊[1] 崔海洋[1] 靳博[1] 曹玮[1] 刘潇潇[1] 

机构地区：[1]北京市西城区疾病预防控制中心,北京100120

出　　处：《公共卫生与预防医学》2017年第5期42-45,共4页Journal of Public Health and Preventive Medicine

基　　金：北京市西城区卫计委青年科技人才培养项目(XWKX2016-17)

摘　　要：目的了解北京地区婴幼儿急性腹泻病例5种腹泻相关病毒的感染状况。方法采集北京地区哨点医院2016年1~12月<60月龄急性腹泻患儿便标本,用实时荧光PCR对A组轮状病毒、诺如病毒、肠道腺病毒、星状病毒进行检测;同时用巢式PCR检测人博卡病毒。结果共采集354份粪便标本,A组轮状病毒检出率13.84%,诺如病毒检出率10.45%,肠道腺病毒检出率4.52%,星状病毒检出率3.95%,人博卡病毒检出率7.34%。混合感染18例,占5.08%。轮状病毒发病高峰为冬季,诺如病毒的发病高峰为春季,其他病毒感染无明显季节特征。2岁以内患儿5种病毒的检出率分别为81.63%、78.38%、81.25%、71.43%、84.62%。结论北京地区急性腹泻患儿5种腹泻相关病毒检出率从高到低依次为:A组轮状病毒、诺如病毒、人博卡病毒、肠道腺病毒、星状病毒;2岁以内患儿是病毒性腹泻的高发人群。Objective To investigate the infection status of the five diarrhea-related viruses among the acute infantile diarrhea casesin Beijing. Methods Stool samples of infantile diarrhea cases of under 60 months old were collected from sentinel hospitals ofBeijing from January to December,2016 ,and tested for group A rotavirus, norovirus,enteric adenovirus and astrovirus by real-time PCR. In addition, the stool samples were also tested for human bocavirus by nested - PCR. Results Among the 354 stool samples, the detection rates of group A rotavirus, norovirus, enteric adenovirus, astrovirus and human bocavirus were 13. 84% , 10. 45% ,4. 52% , 3. 95 %,and 7. 34 % , respectively. Mix - infection was found in 18 cases, accounted for 5 .0 8%. The peak incidence of rotavirus was in Winter,the peak incidence of norovirus was in Spring,while the other viruses had no obvious seasonal peak feature. The detection rates of the 5 viruses among cases under 2 years old were 81.63% ,78. 38% ,81.25% ,71.43% ,and 84. 62% Respectively. Conclusions The detection rates of the 5 viruses among acute infantile diarrhea cases in Beijing was in turn： group A rotavirus, norovirus, human bocavirus, adenovirus and astrovirus. Infants under 2 years old were the high-risk group of viral-diarrhea.

关 键 词：病毒性腹泻 轮状病毒 诺如病毒 肠道腺病毒 星状病毒 人博卡病毒 

分 类 号：R725.7[医药卫生—儿科]