A new approach for identification of medicinal almonds by fourier transform infrared spectroscopy and systematic clustering of characteristic peaks  

作　　者：CHENG Chun-Song WANG Can-Jian LIANG Jie LAO Chi-Chou ZHOU Hua ZHANG Zhi-Feng 

机构地区：[1]State Key Laboratory of Quality Research in Chinese Medicine (Macao University of Science and Technology), Macao 999078,China [2]Faculty of Chinese Medicine, Macao University of Science and Technology, Macao 999078, China [3]Macao Institute for Applied Research in Medicine and Health, Macao 999078, China

出　　处：《Chinese Journal of Natural Medicines》2017年第9期703-709,共7页中国天然药物（英文版）

基　　金：supported by the Macao Science and Technology Development Fund(No.037/2014/A1)

摘　　要：Medicinal almonds have been used for over 2 000 years and its clinical efficacy includes relieving cough and asthma. The domestic market in China is flooded with different kinds of dried almonds, such as bitter almond(Armeniacae Semen Amarum, AAS),sweet almond(Armeniacae Semen Dulce, ADS), salted almond(Armeniacae Semen Salsa, ASS), and their sulfur-fumigating products(Armeniacae Semen Sulphur Fumabat, ASFS). Wide varieties of almonds may lead to uncertain efficacy, aberrant quality, and even increased safety risk. However, the authentication method for medicinal almonds has not been reported, although imposters may lead to ineffective medical response. In the present study, Fourier transform infrared spectroscopy(FTIR) and the 2-dimensional infrared(2 D-IR) spectroscopy were used to identify different almonds, which were extracted with different solvents including water, methanol, ethanol, chloroform and ethyl acetate, respectively. A new simple FTIR method was developed in the present study. According to the gradient solvent polarity, a new 2 D IR method was first developed, and the commodities of almonds in China were analyzed by using the FTIR spectroscopy supported by hierarchical clustering of characteristic peaks. Moreover, 5-hydroxymethyl-2-furfural could be used as a detection index and control target in the quality control of medicinal almonds.Medicinal almonds have been used for over 2 000 years and its clinical efficacy includes relieving cough and asthma. The domestic market in China is flooded with different kinds of dried almonds, such as bitter almond（Armeniacae Semen Amarum, AAS）,sweet almond（Armeniacae Semen Dulce, ADS）, salted almond（Armeniacae Semen Salsa, ASS）, and their sulfur-fumigating products（Armeniacae Semen Sulphur Fumabat, ASFS）. Wide varieties of almonds may lead to uncertain efficacy, aberrant quality, and even increased safety risk. However, the authentication method for medicinal almonds has not been reported, although imposters may lead to ineffective medical response. In the present study, Fourier transform infrared spectroscopy（FTIR） and the 2-dimensional infrared（2 D-IR） spectroscopy were used to identify different almonds, which were extracted with different solvents including water, methanol, ethanol, chloroform and ethyl acetate, respectively. A new simple FTIR method was developed in the present study. According to the gradient solvent polarity, a new 2 D IR method was first developed, and the commodities of almonds in China were analyzed by using the FTIR spectroscopy supported by hierarchical clustering of characteristic peaks. Moreover, 5-hydroxymethyl-2-furfural could be used as a detection index and control target in the quality control of medicinal almonds.

关 键 词：FTIR Almonds Xingren Sulfur-fumigation 

分 类 号：R917[医药卫生—药物分析学]