缓解期风火候偏头痛患者脑白质DTI的TBSS分析  

A study in migraine patients of feng huo syndrome based on the diffusion tensor imaging TBSS analysis

作　　者：李保朋[1] 杨军[2] 韩坤锜 刘晋[4] 吴宏赟[5] 李春林[5] 

机构地区：[1]山东中医药大学附属医院放射科,山东济南250014 [2]中国人民解放军第81医院,江苏南京210002 [3]山东省日照市中医医院,山东日照276800 [4]山东省警官总医院,山东济南250002 [5]山东中医药大学附属医院脑病科,山东济南250014

出　　处：《医学影像学杂志》2017年第10期1845-1849,共5页Journal of Medical Imaging

基　　金：山东省自然科学基金项目(编号:ZR2014CL013);山东省科学基金培养基金项目(编号:ZR2015HL106)

摘　　要：目的探讨缓解期风火候偏头痛患者脑DTI特点及其脑白质结构的改变。方法收集23例偏头痛风火候患者与25名健康志愿者的DTI图像,通过PANDA处理软件,进行基于纤维束追踪空间统计分析(tract-based spatial statistics,TBSS)分析,观察患者组与健康志愿者在大脑功能及结构上的差异。结果相对于对照组,风火候偏头痛组患者5个脑区的FA值在显著降低(P<0.05),分别为胼胝体、右侧扣带回、右侧枕叶、右侧颞叶、右侧小脑。结论相对于对照组,风火候偏头痛组部分脑区的白质结构已经发生改变。Objective To study the DTI characteristics of migraine patients with feng huo syndrome,and to explore the changes of white matter fibers in migraine patients. Methods Twenty three migraine patients and twenty five healthy volunteers underwent DTI scanning. The DTI data were analyzed by PANDA treatment software based on tract-based spatial statistics（ TBSS）analysis. Results Compared with the control group,there were five brain areas of migraine patients with feng huo syndrome with FA values decreased（ P〈0. 05）,which were corpus callosum,right cingulate gyrus,right occipital lobe,right temporal lobe,right cerebellum. Conclusion Compared with the control group,the FA value of multiple brain regions decreased,suggesting that the microstructure of the related brain area of migraine patients with feng huo syndrome had changed.

关 键 词：偏头痛 风火候 弥散张量成像 部分各向异性 纤维追踪技术空间统计方法 

分 类 号：R445.2[医药卫生—影像医学与核医学] R742[医药卫生—诊断学]