424例肺炎婴儿血清维生素D水平分析  

ANALYSIS OF SERUM VITAMIN D LEVEL IN INFANTS WITH PNEUMONIA OF 424 CASES

作　　者：阮银凤 郑敏 

机构地区：[1]柳州市妇幼保健院儿科,广西柳州545001

出　　处：《承德医学院学报》2017年第6期473-476,共4页Journal of Chengde Medical University

基　　金：广西卫生厅科研课题(Z2013609);柳州市科学研究与技术开发计划课题(2014J030421)

摘　　要：目的:分析婴儿肺炎患儿血清维生素D的水平。方法:2015年1月至12月我院收治的424例肺炎婴儿作为病例组,根据月龄分为4组;以同期在我院健康体检的624例健康婴儿作为对照组。采用酶联免疫法检测两组婴儿血清25-(OH)D水平,以25-(OH)D<50.0nmol/L为维生素D缺乏。结果:肺炎婴儿血清25-(OH)D水平明显低于健康婴儿(P<0.01);并且,1-3月龄、4-6月龄、10-12月龄肺炎婴儿血清25-(OH)D水平明显低于同月龄健康婴儿(P<0.01,P<0.05)。肺炎婴儿维生素D缺乏率(52.36%,222/424)明显高于健康婴儿(30.59%),组间比较差异具有统计学意义(P<0.01)。结论:维生素D缺乏的婴儿可能更易患肺炎;肺炎患儿和健康婴儿均应注重补充维生素D。Objective： To analyze the serum vitamin D level in infants with pneumonia. Methods： 424 cases of pneumonia infants in our hospital form 2015.1 to 2015.12 were taken as case group and divided into 4 groups according to months of age; 644 healthy infants were taken as control group in our hospital at the same term. Euzymelinked immunosorbent assay was used to detect the serum 25-（OH）D level of all infants. Results： The serum 25-（OH）D level of pneumonia infants was obviously lower than healthy infants（P〈0.01）; And, the serum 25-（OH）D level of pneumonia infants of 1-3 months, 4-6 months and 9-12 months were all obviously lower than the same age healthy infants（P〈0.01, P〈0.05）. The incidence of vitamin D deficiency in pneumonia infants was 52.36%（222/424）, which was significantly higher than healthy infants（30.59%, P〈0.01）. Conclusions： Infants with vitamin D deficiency maybe more likely to suffer pneumonia; Pneumonia infants and healthy infants all should pay attention to vitamin D supplementation.

关 键 词：维生素D 维生素D缺乏 婴儿肺炎 月龄 

分 类 号：R723[医药卫生—儿科]