非肥胖2型糖尿病与非酒精性脂肪性肝病相关性的Meta分析  

The relationship between non-obesity type 2 diabetes mellitus and non-alcoholic fatty liver disease: a Meta-analysis

作　　者：党超志[1] 唐超燕 

机构地区：[1]广西玉林市第一人民医院内分泌科,广西玉林537000

出　　处：《胃肠病学和肝病学杂志》2017年第10期1128-1131,共4页Chinese Journal of Gastroenterology and Hepatology

摘　　要：目的通过Meta分析评估非肥胖2型糖尿病与非酒精性脂肪性肝病(non-alcoholic fatty liver disease,NAFLD)相关性,旨在为非肥胖2型糖尿病与NAFLD的相关性提供循证医学依据。方法检索Medline、Pub Med、EMBASE、CBM、中国知网、万方、维普、学术会议资料和学位论文等数据库,全面收集关于非肥胖2型糖尿病与NAFLD相关的队列研究和病例对照文献,确定非肥胖2型糖尿病是否与NAFLD相关。应用Stata 11.0软件进行Meta分析。结果共纳入10项非肥胖2型糖尿病与NAFLD相关研究。Meta分析结果显示,非肥胖2型糖尿病与NAFLD相关患病风险具有重要关联性,其中显性固定效应模型OR=1.653(95%CI:1.416~1.930);共显性的固定效应模型OR=1.525(95%CI:1.350~1.723)。结论通过Meta分析得出,非肥胖2型糖尿病与NAFLD具有相关性。Objective To assess the association between non-obese type 2 diabetes and non-alcoholic fatty liver disease（ NAFLD） by Meta-analysis,and to provide evidence-based evidence for the association between non-obese type2 diabetes and NAFLD. Methods The data of cohort studies and case-control studies about the relationship between non-obesity type 2 diabetes mellitus and NAFLD by retrieving collected Medline,Pub Med,EMBASE,CBM,CNKI,Wangfang data,VIP,academic conference materials and dissertations were searched. Stata 11. 0 software was used to perform Meta-analysis. Results A total of 10 non-obesity type 2 diabetics associated with NAFLD. Meta-analysis showed that non-obesity type 2 diabetes was related with NAFLD included dominant fixed effect model（ OR = 1. 653,95% CI： 1.416-1.930）; co-dominant fixed effect model（ OR = 1.525,95% CI： 1.350-1.723）. Conclusion Non-obesity type 2 diabetes mellitus is associated with NAFLD by Meta-analysis.

关 键 词：2型糖尿病 非肥胖 非酒精性脂肪性肝病 META分析 

分 类 号：I575.5[文学—其他各国文学]