DWI鉴别良、恶性肺结节准确性探讨  

Investigation the Accuracy of DWI in the Identifying of Benign and Malignant Solitary Pulmonary Nodules

作　　者：陈洪[1] 曾浩[1] 沈小程 胡纳[1] 王辉[1] 

机构地区：[1]四川省遂宁市中心医院,四川遂宁629000

出　　处：《中国医学创新》2017年第28期121-124,共4页Medical Innovation of China

摘　　要：目的:分析不同b值下DWI鉴别良、恶性肺结节准确性以及临床价值。方法:选取2015年12月-2016年12月本院接收的72例SPN者为研究样本,将其分为恶性组42例和良性组30例。对患者进行常规化T1WI,T2WI和DWI扫描,比较两组患者在不同b值时ADC值变化以及信号强度情况。结果:当b=500 s/mm^2时,两组ADC值比较差异有统计学意义(P<0.05);当b=800~1000 s/mm^2时,少数SPN于ADC图像上无法测定出具体值,良性组中7例ADC的均值为0,恶性组中8例为0。当b=300~1000 s/mm^2时,两组信号强度比较差异均有统计学意义(P<0.05)。结论:DWI对于良、恶性SPN鉴别诊断有临床意义,结节信号水平诊断效能比ADC值高,DWI可视为一种重要的辅助诊断方式,值得进一步在临床中推广使用。Objective：To analysis the accuracy and clinical value of DWI for differential diagnosis of benign and malignant SPN under different b values.Method：72 cases of SPN were treated in our hospital from December 2015 to December 2016 were selected as research subjects,they were divided into the malignant group of 42 cases and benign group of 30 cases.Routine T1WI,T2WI and DWI scans were performed,the changes of ADC values and the signal intensity of SPN in different b values of two groups were compared.Result：When the b=500 s/mm2,compared the ADC value of two groups,the difference was statistically significant（P〈0.05）;when the b=800-1000 s/mm2,a small number of SPN on the ADC image could not determine the specific value,the mean of 7 cases of ADC in the benign group was 0,and the 8 cases of malignant group was 0.When b=300-1000 s/mm2,the signal strength of two groups were compared,the differences statistically significant（P〈0.05）.Conclusion：DWI can provide clinically meaningful information for SPN diagnosis and differential diagnosis of malignant and benign nodules,the diagnosis efficiency value of signal level is higher than ADC,DWI can be regarded as an important auxiliary diagnostic method,it is worthy of further promotion in clinical use.

关 键 词：磁共振成像 加权扩散成像 孤立性肺结节 B值 准确性 

分 类 号：R445.2[医药卫生—影像医学与核医学] R734.2[医药卫生—诊断学]