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机构地区:[1]兰州军区兰州总医院,730050 [2]河南大学淮河临床医学院,开封475000 [3]兰州军区兰州总医院全军骨科中心,730050
出 处:《中华生殖与避孕杂志》2017年第9期746-749,共4页Chinese Journal of Reproduction and Contraception
基 金:国家自然科学基金(81371983)~~
摘 要:目的探讨连续性肾脏替代治疗(continuous renal replacement therapy,CRRT)对HELLP综合征(hemolysis,elevated liver enzymes,and low platelets syndrome)的治疗作用。方法对1名40岁,第二次自然妊娠,双胎,剖宫产后大出血随后发展为HELLP综合征并出现多器官功能障碍综合征(MODS)的女性患者,进行院内ICU救治并给予连续性肾脏替代治疗(CRRT)。结果经治疗36 d后,患者好转出院,后电话随访,未再出现相关不适症状。结论肾上腺糖皮质激素及CRRT的应用提高了HELLP综合征患者的生存率及生活质量,但应用的时机和剂量还需要大规模的研究。Objective To investigate the effect of continuous renal replacement therapy(CRRT) of hemolysis elevated, liver enzymes, and low platelets syndrome(HELLP syndrome) treatment. Methods Hospital ICU treatment and CRRT were performed in the female patient of 40-year old, second natural twin pregnancy, cesarean section, postpartum hemorrhage and development for HELLP and the multiple organ dysfunction syndrome(MODS). Results After treatment for 36 d, the patient was discharged from the hospital, and after telephone followup, there was no related symptoms. Conclusion The application of adrenal glucocorticoid and CRRT improve the survival and living quality of patients with HELLP syndrome, but the timing and dose of the application also require a large-scode study.
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