人类卵巢组织异种移植的影响因素及研究进展  

Influencing factors and research progress of the human ovarian tissue xenotransplantation

作　　者：王琳[1] 徐键[1] 

机构地区：[1]浙江大学医学院附属妇产科医院,杭州310006

出　　处：《中华生殖与避孕杂志》2017年第9期767-772,共6页Chinese Journal of Reproduction and Contraception

摘　　要：人类卵巢组织异种移植目前已广泛用于观察卵泡的发育和评估卵巢冷冻等其他相关保存女性生育能力措施的一种实验手段。有许多因素影响移植的效果,如动物受体、卵巢组织的准备、移植后血管的形成、促性腺激素的使用等。虽然目前的研究表明,卵巢组织异种移植技术能保护女性的生育能力、恢复卵巢内分泌和生殖功能,但是,由于安全和伦理的限制它目前只在实验条件下进行。本文对影响人卵巢组织异种移植的因素及近年来的研究进展作一综述。Human ovarian tissue xenotransplantation emerges as widely used experimental animal model to investigate the various aspects of follicle development and the effect of other related interventions of fertility preservations such as cryopreservation. There are many factors influence the effect of xenotransplantation, such as animal recipient, ovarian tissue preparation, vascular supply after transplantation and the use of gonadotropins.Although there is some evidence that this procedure might be effective in preservation of future female fertility and restoring ovarian endocrine and reproductive function, it should only be performed under experimental conditions,until the technique is found to be safe and ethical. This article reviews the factors affecting the xenotransplantation of human ovarian tissue and the recent progress in this paper.

关 键 词：异种移植 人类 卵巢组织 

分 类 号：R713[医药卫生—妇产科学]