合肥地区部分健康人群面颈部皮肤生理学与VISIA成像特征分析  

Study between physiological properties and image features of nomale faciocervical skin

作　　者：陈丽云 盛宇俊[1,2] 高金平 杨森[1,2] 

机构地区：[1]安徽医科大学第一附属医院皮肤科,合肥230022 [2]安徽医科大学皮肤病研究所,合肥230032

出　　处：《安徽医科大学学报》2017年第11期1685-1689,共5页Acta Universitatis Medicinalis Anhui

基　　金：国家自然科学基金(编号:81361128014)

摘　　要：目的通过无创性检测技术量化合肥地区部分正常人群面颈部皮肤生理学特性和成像特征,分析其与性别、年龄的关系。方法将500例健康志愿者分为6个不同年龄组,采用无创性皮肤生理检测仪对其面颈部(前额、面颊及颈部)进行角质层(SC)含水量、皮脂含量、经表皮水分流失量(TEWL)及皮肤色素含量的测量,并采用VISIA-CR面部成像系统评估皱纹、紫外线色斑及皮肤SC含水量之间的相关性。结果 (1)女性面颈部SC含水量高于男性,男性面颈部TEWL值、皮脂及色素含量高于女性(P<0.05);(2)SC含水量与年龄呈负相关性,TEWL值在5~15岁和56~70岁年龄组均较低(P<0.05);(3)皮肤皱纹、紫外线色斑和纹理与年龄呈正相关性,紫质分值与毛孔大小呈正相关性(P<0.05);(4)女性前额部皱纹与TEWL呈正相关性,紫外线色斑与SC含水量呈负相关性(P<0.05)。结论通过定量测量面颈部皮肤生理特性和成像特征,分析相关参数及其关系,能够客观地评估皮肤年轻化、衰老速度及敏感程度,评估医学美容对皮肤屏障的修复状态。Objective To quantity the physiological properties and the image features of faciocervical skin in Hefei narmal population, and to analyze their relationship between sex and age. Methods 500 healthy volunteers in 5 age groups were enrolled in this study. A multifunctional skin physiology monitor （Courage ＆ Khazaka electronic GmbH, Germany） was used to measure skin sebum content （SC） hydration, transepidermal water loss （TEWL） , erythema index and melanin index in 3 different locations of the face. Facial images （wrinkle volume, roughness and UV spots ） were photographed by VISIA-CR. Results There were significant differences between the hydra- tion, TEWL, erythema index and melanin index of different age groups （ P 〈 0. 05 ）. The mean values of TEWL, SC hydration, erythema index, melanin index, wrinkle volume and roughness were significantly higher in males（P 〈 0. 05 ）. On the forehead skin of females, a positive correlation was found between TEWL and wrinkle volume （P 〈 0. 05 ）. A negative correlation was found between SC hydration and UV spots （P 〈 0. 05 ）. Conclusion Non-in- vasive technique can explore the variations in several skin physiology and images in different gender and age groups. These differences can describe the skin features and provide effective treatment for some skin disease.

关 键 词：面颈部 性别 年龄 SC含水量 TEWL 

分 类 号：R473.6[医药卫生—护理学]