慢咽舒丸质量标准研究  

Quality Standard of Manyanshu Pill

作　　者：彭柳 龚大春[2] 范开静 汪冬妮 

机构地区：[1]三峡食品药品检验检测中心,湖北宜昌443005 [2]三峡大学,湖北宜昌443002 [3]宜都市第一人民医院,湖北宜昌443300

出　　处：《亚太传统医药》2017年第21期8-11,共4页Asia-Pacific Traditional Medicine

摘　　要：目的:建立慢咽舒丸的质量标准。方法:采用薄层色谱法对桔梗、枳壳进行定性鉴别,采用高效液相色谱法测定葛根素的含量。结果:定性鉴别薄层色谱特征明显,专属性强,空白对照无干扰,阴性对照无干扰;葛根素在7.529~376.5μg·mL^(-1)范围内线性关系良好(r=0.999 9,n=7),平均回收率为98.34%,RSD=0.4%(n=6)。结论:该标准可有效控制慢咽舒丸的质量。Objective:To establish quality specifications of Manyanshu pill,ensuring clinical efficacy.Methods:TLC was performed to identify Chinese bellflower,Fructus aurantii,HPLC was used to determine Puerarin content.Results:The characteristic of identification by TLC was distinct and highly specific.The quantification method had the linearity range of 7.529~376.5μg/mL(r=0.9999,n=7).The average recovery was 98.34%,RSD = 0.4%(n=6).Conclusion:It can be used for the quanlity control of manyanshu pill.

关 键 词：慢咽舒丸 质量标准 TLC HPLC 

分 类 号：R288[医药卫生—中药学]