儿童精神分裂症患者出院5年内再入院影响因素研究  

A study of impact factors on readmission of childhood-onset schizophrenics in 5 years after discharge

作　　者：杨楹[1] 程小菁[1] 刘金同[1,2] 

机构地区：[1]山东省精神卫生中心,济南250014 [2]山东大学医学院,济南250014

出　　处：《济宁医学院学报》2017年第5期342-345,共4页Journal of Jining Medical University

基　　金：山东省科技发展计划项目(2012YDI8061)

摘　　要：目的观察儿童精神分裂症患者出院后5年内复发再入院的情况,探索影响儿童精神分裂症患者再入院的预测因素,为改善儿童精神分裂症的预后提供科学依据。方法以在山东省精神卫生中心儿童青少年病区收集的儿童首发精神分裂症住院患者81例作为研究对象,采用自制患者一般情况调查量表、病前社会适应能力评估量表(Promorbid Adjustment Scale,PAS)、阳性症状与阴性症状量表(The Positive and Negnitive Syndrome Scale,PANSS)及自制门诊随访情况调查表,前瞻性随访5年,观察儿童精神分裂症患者的再入院情况,进行再入院影响因素的分析。结果 COX回归分析发现,基线时兴奋敌对因子得分高、服药依从性差及更改治疗方案次数多是精神分裂症患者出院后5年内再住院的危险因素。结论儿童精神分裂症患者再住院的高危人群为发病时兴奋敌对程度高、不能坚持服药、频繁换药者,我们应重视这些高危群体,及早干预,尽可能地降低儿童精神分裂症再入院率。Objective To carry out a five-year follow-up with child patients with schizophrenia by standardized assessment tool and observe readmission and explore the related predictors. Methods 81 childhood-onset first-episode schizophrenics were recruited who were admitted to Shandong mental health center. With Self-made General Condition Survey List,Modified Promorbid Adjustment Scale,Positive and Negative Syndrome Scale,Personal and Social Performance Scale,the data were collected with readmission time and related factors such as demographics,medication compliance,medication conversion during 5-year follow-up. Results It showed that excitement score,medication compliance and frequent medication conversion were predictors for readmission. Conclusion We should attach great importance to the risk factors and take effective measures to reduce readmission.

关 键 词：儿童精神分裂症 再住院 影响因素 

分 类 号：R749.3[医药卫生—神经病学与精神病学]