肾脏损伤后成体干细胞修复的研究进展  

Advances of adult stem cell repair in renal injury

作　　者：吴暄 郭义峰[1] 

机构地区：[1]上海市第一人民医院泌尿外科,临床医学中心泌尿移植科,上海200080

出　　处：《中国医师杂志》2017年第10期1594-1598,共5页Journal of Chinese Physician

基　　金：国家自然科学基金（81370342）

摘　　要：至今对于急性或慢性肾脏损伤仍缺乏较好的治疗方式。人体肾脏的组织结构虽复杂，但可通过新生细胞所代替死亡的肾小管上皮细胞修复肾脏损伤。随着细胞增殖及多向分化潜能的特性用于疾病治疗的研究逐渐深入，也有了利用干细胞治疗肾脏的治疗思路。本文对成体干细胞于肾脏再生特点的进行论述，并简述在病理情况下的修复再生的作用。Acute and chronic kidney injury are still lack of good treatments now. Although human renal histological structure is complex, it also can be regenerated by new renal tubular epithelial cells repla- cing injured ceils. With the study deepening, it supports a new way for treating kidney injury with charac- teristics of proliferation and differentiation of stem cells. This article will discuss the features of some kinds of the adult stem cells in the kidney regeneration, and those functions in the pathological situation briefly.

关 键 词：肾疾病/外科学 肾/损伤 干细胞移植 综述 

分 类 号：R692[医药卫生—泌尿科学]