注射用丹参多酚酸盐对老年不稳定型心绞痛患者临床疗效及QT离散度的影响  

Clinical efficacy of salvianolate injection on elderly patients with unstable angina pectoris and its influence on QT dispersion

作　　者：张立娟[1] 李玉荣[1] 

机构地区：[1]沈阳市第四人民医院干诊科,110031

出　　处：《中国现代药物应用》2017年第20期89-91,共3页Chinese Journal of Modern Drug Application

摘　　要：目的探讨注射用丹参多酚酸盐对老年不稳定型心绞痛患者临床疗效及QT离散度(QTd)的影响。方法 120例老年不稳定型心绞痛患者,按随机数字表法分为对照组(55例)和治疗组(65例),对照组给予常规西药治疗,治疗组在对照组基础上加用注射用丹参多酚酸盐治疗。比较两组治疗方案对老年不稳定型心绞痛患者临床疗效及QTd的影响。结果治疗组总有效率为92.31%,高于对照组的76.36%,差异有统计学意义(χ2=5.94,P<0.05)。治疗前,两组患者QTd比较,差异无统计学意义(P>0.05);治疗后,两组患者QTd均较本组治疗前缩小,且治疗组缩小幅度大于对照组,差异有统计学意义(P<0.05)。结论在常规药物治疗基础上加用注射用丹参多酚酸盐治疗老年不稳定型心绞痛能取得更满意的临床疗效,并可降低QTd,值得推广。Objective To discuss the clinical efficacy of salvianolate injection on elderly patients with unstable angina pectoris and its influence on QT dispersion（QTd）. Methods A total of 120 elderly patients with unstable angina pectoris were divided by random number table method into control group（55 cases） and treatment group（65 cases）. The control group was treated with conventional western medicine, and the treatment group was treated with salvianolate injection on the basis of the conventional therapy. Comparison were made on clinical efficacy and its influence on QTd between two groups. Results The treatment group had higher total effective rate as 92.31% than 76.36% in the control group, and the difference was statistically significant（2=5.94, P〈0.05）. Before treatment, both groups had no statistical significance in QTd（P〉0.05）. After treatment, both groups had shorter QTd, but the treatment group had larger shortening range than the control group. Their difference was statistically significant（P〈0.05）. Conclusion Application of salvianolate injection o the basis of conventional drug therapy in the treatment of elderly unstable angina pectoris can achieve more satisfactory clinical efficacy, and can reduce QTd. It is worth promoting.

关 键 词：注射用丹参多酚酸盐 QT离散度 老年不稳定型心绞痛 

分 类 号：R541.4[医药卫生—心血管疾病]