高频电离子联合Medlite激光治疗先天性色痣疗效观察  

Clinical effect of high frequency electric ion combined with Medlite laser on congenital pigmented nevus

作　　者：张力军[1] 张高明[1] 高建芳 白凤祥 马翠玲[2] ZHANG Lijun ZHANG Gaoming GAO Jianfang BAI Fengxiang MA Cuiling(Department of Dermatology, Affiliated Hospital, Air Force Aviation Medical Research Institute, Beijing 100089, China Department of Dermatology, Xijing Hospital, the Fourth Military Medical University, Xi＇an 710038, China)

机构地区：[1]空军航空医学研究所附属医院皮肤科,北京100089 [2]第四军医大学西京医院皮肤科,陕西西安710038

出　　处：《中国医学物理学杂志》2017年第10期1041-1044,共4页Chinese Journal of Medical Physics

基　　金：国家自然科学基金(81672691)

摘　　要：目的:观察应用高频电离子联合Medlite C6激光治疗先天性色痣的临床疗效。方法:采用高频电离子联合Medlite C6激光治疗先天性色痣患者134例。根据治疗方法分为3组,A组为高频电离子组(n=42),B组为Medlite C6激光组(n=40),C组为高频电离子和Medlite C6联合治疗组(n=52)。各组根据年龄、皮肤颜色选择不同的技术参数进行治疗,每次间隔3个月以上。结果:患者治疗1次38例,治疗2次67例,治疗3次以上29例。治疗后随访0.5~1年,134例患者中痊愈45例(33.6%),显效36例(26.9%),好转33例(24.6%),无效20例(14.9%),总有效114例(85.1%)。C组总有效率达96.2%(50/52),明显优于A组的81.0%(34/42)和B组的75.0%(30/40),其差异具有统计学意义(P<0.05)。治疗过程未发生明显不良反应。结论:高频电离子联合Medlite C6激光是选择性治疗先天性色痣的一种安全、有效和快速方法。Objective To investigate the therapeutic effect of congenital pigmented nevus（CPN） treated with high frequency electric ion combined with Medlite C6 laser. Methods The 134 patients with CPN were divided into 3 groups for the treatment with high frequency electric ion（group A, n=42）, Medlite laser（group B, n=40）, and high frequency electric ion combined with Medlite C6 laser（group C, n=52）. The technical parameters were determined according to patients＇ age and skin color. Each interval of treatment was 3 months or longer. Results In 134 cases, 38 cases received only one treatment; 67 cases underwent two treatments;29 cases were treated more than 3 times. The follow up for 0.5-1.0 year showed that 45 cases were cured（33.6%）, and 36 cases were markedly effective（26.9%）, and 33 cases improved（24.6%）, and 20 cases were ineffective（14.9%）. The total effective rate was 85.1%（114/134）. In group C, the total effective rate was 96.2%（50/52）, obviously higher than 81.0% in group A（34/42）and 75.0% in group B（30/40）, with statistical significance（P〈0.05）. No obvious adverse reactions occurred during the treatment.Conclusion High frequency electric ion combined with Medlite C6 laser is a safe, effective and rapid method for the treatment of CPN.

关 键 词：高频电离子 MEDLITE C6激光 先天性色痣 

分 类 号：R751.51[医药卫生—皮肤病学与性病学] R318.51[医药卫生—临床医学]