2016年上海市黄浦区疑似预防接种异常反应监测结果  

Surveillance results of adverse events following immunization in Huangpu District of Shanghai in 2016

作　　者：王婧[1] 姜铭波[1] 陆瑾[1] 周文瑜[1] 张国华[1] 严玲[1] 何景雄[1] WANG Jing JIA NG Ming-bo LU Jin ZH OU Wen-yu ZHA NG Guo-hua YA N Lin HE Jing-xiong(Department of Immunization Planning, Shanghai Huangpu Center for Disease Control and Prevention, Shanghai, 200023, Chin)

机构地区：[1]上海市黄浦区疾病预防控制中心免疫规划科,上海200023

出　　处：《职业与健康》2017年第20期2828-2830,2833,共4页Occupation and Health

摘　　要：目的分析2016年上海市黄浦区疑似预防接种异常反应(AEFI)的报告情况和发生特征。方法通过全国AEFI信息管理系统(AEFIIMS),收集2016年1月1日—12月31日黄浦区报告的个案数据,采用描述性方法对相关指标进行分析。结果 2016年,黄浦区共报告AEFI个案305例,男女比例为1.21∶1;年龄分布,<1岁104例,占34.10%;1~2岁109例,占35.74%;3~6岁62例,占20.33%;≥7岁30例,占9.84%。报告发生率为183.80/10万,报告发生AEFI前3位的疫苗为:百白破疫苗(无细胞)63例(占20.66%),百白破IPV和Hib五联疫苗55例(占18.03%)和白破疫苗(儿童)52例(占17.05%)。接种第1剂次后发生的127例(占41.64%),接种后≤1 d发生的229例(占75.08%)。AEFI分类诊断中,一般反应270例(占88.52%),异常反应35例(占11.48%),所有个案转归为痊愈。结论黄浦区应开展针对新疫苗的AEFI主动监测,以便更为有效的评价新疫苗的安全性。与此同时,还需要通过培训和建立激励机制等方式加强队伍建设,提高AEFI的监测水平。[Objective]To analyze the report status and occurrence features of adverse events following immunization（AEFI） in Huangpu District of Shanghai in 2016.[Methods]The AEFI data from January 1 to December 31 in 2016 in Huangpu District were collected through AEFI Information Management System（AEFIIMS） and analyzed by descriptive methodology.[Results]Totally305 AEFI cases were reported in 2016 in Huangpu District,with the male-to-female ratio of 1.21 ∶ 1. The age distribution showed that there were 104（34.1%）cases in 1 year old group,109（ 35.74%）cases in 1-2 year-old group,62（20.33%）cases in 3-6 year-old group,and 30（9.84%）cases in≥7 year-old group. The reported incidence rate was 183.80 per 100 000 doses. The first three vaccines were DTP（63 cases,20.66%）,DTP-IPV-Hib vaccine（55 cases,18.03%） and DT（52 cases,17.05%）. 127（41.46%）cases were reported after the first dose,and 229（75.08%）cases were reported within the first day after vaccination.AEFI classification diagnosis showed that there were 270（88.52%）cases of common reaction and 35（11.48%）cases of abnormal reaction,and all cases were cured.[Conclusion]It is necessary to carry out the active AEFI surveillance on new vaccines to effectively evaluate the safety of the new vaccines,and strengthen the team building through training and the establishment of incentive mechanisms,so as to improve the monitoring level of AEFI.

关 键 词：疑似预防接种异常反应 监测 

分 类 号：R186[医药卫生—流行病学]