老年休克性肺炎患者早期全血NT-proBNP水平的临床意义  

Clinical significance of early whole blood NT-proBNP levels in elderly patients with shock pneumonia

作　　者：陆高峰[1] LU Gao-feng.(Department of Critical Care Medicine, Suzhou City Wuzhong People＇s Hospital, Suzhou 215128, China)

机构地区：[1]苏州市吴中人民医院重症医学科,215128

出　　处：《中国实用医药》2017年第29期14-16,共3页China Practical Medicine

摘　　要：目的探讨老年休克性肺炎患者早期全血氨基末端脑钠肽前体(NT-proBNP)水平的临床意义。方法 19例老年休克性肺炎患者,根据患者治疗10 d后的转归情况分为好转组(8例)和恶化组(11例)。分析两组患者早期NT-proBNP水平。结果两组患者平均年龄、入科24 h的急性生理功能和慢性健康状况评分系统Ⅱ(APACHEⅡ)评分比较,差异无统计学意义(t=1.390、1.312,P>0.05)。两组患者治疗初始时血浆NT-proBNP水平比较,差异具有统计学意义(P<0.05)。结论检测老年休克性肺炎患者治疗初始全血NT-proBNP水平对短期疗效的判断有一定临床意义,值得临床重视。Objective To investigate the clinical significance of early whole blood N-terminal pro-brain natriuretic peptide（NT-proBNP） levels in elderly patients with shock pneumonia.Methods A total of 19 elderly patients with shock pneumonia were divided by outcomes after 10 d of treatment into improvement group（8 cases） and deterioration group（11 cases）.Early NT-proBNP levels in two groups was analyzed.Results Both groups had no statistically significant difference in mean age,acute physiology and chronic health evaluation Ⅱ（APACHE Ⅱ） score in 24 h of admission（t=1.390,1.312,P〉0.05）.Both groups had statistically significant difference in plasma NT-proBNP of initially treatment（P〈0.05）.Conclusion Detection of early whole blood NT-proBNP in patients with senile shock pneumonia shows certain clinical significance on determination of short-term efficacy,and is worthy of clinical attention.

关 键 词：休克性肺炎 感染性休克 氨基末端脑钠肽前体 

分 类 号：R459.7[医药卫生—急诊医学] R563.1[医药卫生—治疗学]