急性百草枯中毒87例救治分析  

Treatment experience of acute paraquat poisoning： analysis of 87 cases

作　　者：陈士超[1] 孙宝泉[1] 李君[1] 于中锴[1] 赵波[1] Chen Shichao Sun Baoquan Li Jun Yu Zhongkai Zhao Bo(Department of Emergency, the People＇s Hospital of Liaocheng,Liaocheng, Shandong 252000, Chin)

机构地区：[1]聊城市人民医院急诊科,山东省聊城252000

出　　处：《中国基层医药》2017年第21期3307-3310,共4页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的对百草枯中毒的救治体会进行分析，探讨百草枯中毒的预后因素、治疗方案。方法回顾性分析该院急诊科2014-2015年收治的百草枯中毒患者87例的临床资料。结果87例百草枯中毒患者死亡38例，治愈49例，治愈率56．32％；死亡组口服百草枯平均65．3mL，明显高于存活组的41．2mL（t=16．65，P〈0．01）。结论服毒量是影响预后的关键，白细胞明显升高、肺部病变出现早或范围大是预后不良的重要因素；尽早洗胃、导泻并且及时血液净化、应用肾上腺皮质激素、抗氧化等综合治疗可降低病死率。Objective To explore the treatment experience of acute paraquat poisoning, thus to explore the prognostic factors and treatment measures. Methods The clinical data of 87 patients with paraquat poisoning who were treated with combined therapy in our hospital emergency department 2014 -2015 were retrospectively analyzed. Results 49 cases survived and 38 cases were died in 87 paraquat poisoning patients,the survival rate was 56.32%. The average paraquat of the death group was 65.3mL, which was significantly higher than 41.2mL of the survival group（ t = 16.65 ,P 〈 0.01 ）. Conclusion Amount of poisoning is the key to the prognosis, white blood cells were significantly increased, early or large areas of lung disease is an important factor in poor prognosis ; early gastric lavage, cathartic and timely blood purification, application of adrenal cortex hormones, antioxidant and other .compre- hensive treatment can reduce mortality.

关 键 词：百草枯 中毒 治疗 预后 

分 类 号：R595.4[医药卫生—内科学]