中药抗四氯化碳所致急性肝损伤作用研究进展  

Research Progress in the Inhibitory Effect of Traditional Chinese Medicine on Carbon Tetrachloride Induced Acute Liver Injury

作　　者：刘利平[1] 陶旭锋 韩旭[2] 许丽娜[2] Liu Liping Tao Xufeng Han Xu Xu Lina(The First Affiliated Hospital of Dalian Medical University, Liaoning Dalian 116011, China College of Pharmacy, Dalian Medical University)

机构地区：[1]大连医科大学附属第一医院,辽宁大连116011 [2]大连医科大学药学院

出　　处：《中国药师》2017年第9期1638-1642,共5页China Pharmacist

摘　　要：肝脏疾病是一种严重危害人类健康的疾病,四氯化碳(CCl_4)诱导的肝损伤作为经典的急性肝损伤模型,广泛用于保肝药物的筛选。本文综述了近几年国内外中药及制剂对CCl_4所致急性肝损伤保护作用的研究进展,为寻找高效低毒的保肝中药提供依据,也为推进肝病的中药治疗奠定基础。Liver diseases are serious diseases harmful for human health. CCl4 induced liver injury, as a classic liver injury model, has been widely used in the screening of hepatoprotective drugs. This paper reviewed the research progress in the hepatoprotective effect of traditional Chinese medicines （TCMs） on CC14 induced acute liver injury in recent years, which can provide basis for searching TCMs with high efficiency and low toxicity and lay foundation for TCMs in the treatment of liver diseases.

关 键 词：中药 保肝作用 四氯化碳 急性肝损伤 

分 类 号：R285.5[医药卫生—中药学]