艾滋病患者血培养菌型分布及其耐药性  

The new trend of drug sensitivity and bacteria types of blood-culture for AIDS

作　　者：吴开进 WU Kai-jin(The Red Cross Hospital of Yu Lin, Yu Lin, Guangxi 537000, Chin)

机构地区：[1]玉林市红十字会医院,广西玉林537000

出　　处：《热带医学杂志》2017年第10期1311-1313,1321,共4页Journal of Tropical Medicine

摘　　要：目的了解艾滋病(AIDS)患者的血培养菌临床分布特点及所分离菌株耐药新趋势。方法回顾性调查分析玉林市红十字会医院感染科2012年1月至2013年12月收治AIDS患者的血培养结果及临床资料。结果 259例AIDS患者血培养阳性93例,阳性率35.9%,其中10例复数菌感染,分离出17种菌共103株。61株马尔尼菲青霉菌和6株新生隐球菌对一些抗真菌药物敏感性有不同程度下降;12株凝固酶阴性葡萄球菌中有10株为MRCNS;7株大肠埃希菌中有5株产超广谱β内酰胺酶。结论 AIDS患者血流感染中,MRCNS和产超广谱β-内酰胺酶大肠埃希菌比例较高,马尔尼菲青霉菌对一些抗真菌药物敏感性下降。Objective To understand the distribution of blood culture strains in AIDS patients and the new drug-resistant trends of isolated strains. Methods A retrospective analysis was performed on blood culture of AIDS patients adopted in infectious department of our hospital from January 2012 to December 2013. Results 93 cases with positive blood cultures were observed among 259 AIDS positive cases;the positive rate was 35.9%,including 10 cases of complex bacteria infection. 103 strains of 17 kinds of bacteria were isolated. Also,antifungal susceptibility of 61 Penicillium marneffei and 6 Cryptococcus neoformans to some drugs decreased to varying degrees;10 multi-drug resistant Methicillin resistant staphylococcus were observed among 12 coagulase negative staphylococcus. 7 Escherichia coli strains were found to produce Extended-Spectrum β-lactamases. Conclusion Methicillin resistant staphylococcus and Escherichia coli producing Extended-Spectrum β-lactamases hada higher proportion as important infectious bacteria of AIDS patients. Additionally,decreased antifungal susceptibility of Penicillium marneffei should be paid attention to.

关 键 词：血培养 病原菌 感染 药物敏感性试验 

分 类 号：R512.91[医药卫生—内科学]