泛嗜性犬冠状病毒的研究进展  

Review on pantropic canine coronavirus

作　　者：李毅恒[1] 刘凤军[1] 张玉玲[1] 史新怀 赵浩[1] 刘向阳[1] 

机构地区：[1]河南科技大学动物科技学院,河南洛阳471003

出　　处：《黑龙江畜牧兽医》2017年第11期64-67,293,共5页Heilongjiang Animal Science And veterinary Medicine

基　　金：国家自然科学基金项目(30901026);河南省高等学校青年骨干教师资助计划项目(2010GGJS-071)

摘　　要：犬冠状病毒(CCV)是导致犬胃肠道疾病的一种常见病原体,目前CCV已确定了两个基因型,即CCV-Ⅰ和CCV-Ⅱ。一般情况下,CCV会导致犬轻重不一的腹泻,合并感染犬的其他病原体会造成致命性结局。然而,几年前报道出现了一种能够造成犬全身性疾病、致死率很高的变异CCV-Ⅱ强毒株,即泛嗜性犬冠状病毒(CB/05毒株)。到目前为止,已有多个国家报道出现泛嗜性CCV,其临床症状和病理变化与首次报道相似,目前中国还没有泛嗜性CCV报道。文章对泛嗜性CCV的研究进行了综述,并为我国防范该病毒提出建议。Canine eoronavirus （CCV） was a common pathogen which caused canine gastrointestinal disease. At present two genotypes of CCV had been described, CCV - Ⅰ and CCV - Ⅱ. In general CCV could cause different severity of diarrhea in dogs, whereas co - infection with other pathogens could lead to fatal outcome. Whereas, a virulent strain of variant CCV - Ⅱ named CB/05, a pantropic canine coronavirus, was reported several years ago,which caused canine systemic disease and high fatality rate. So far many countries reported pantropic CCV, with clinical sign and pathological changes similar to those in the first report;no findings on pantropic CCV had been found in China. This paper had a review on research on pantropie CCV and could offer a proposal on the control of pantropie CCV in China.

关 键 词：泛嗜性犬冠状病毒 普通肠型犬冠状病毒 病原学 临床症状 病理变化 

分 类 号：S852.659.6[农业科学—基础兽医学]