肝吸虫感染致胆管癌发病机制的研究进展  

Advances in research on the pathogenesis of cholangiocarcinoma caused by liver fluke infection

作　　者：任一鑫[1] 隋春兴[2] 余钢银[3] 秦元华[1] 崔昱[1] REN Yi-xin SUI Chun-xing YU Gang-yin QIN Yuan-hua CUI Yu(Department of Parasi- tology, Dalian Medical University, Dalian 116044, China Cardiology, Dalian Municipal Central Hospital Liaoning Normal University Clinic)

机构地区：[1]大连医科大学寄生虫学教研室,辽宁大连116044 [2]大连市中心医院心内科 [3]辽宁师范大学门诊部

出　　处：《中国病原生物学杂志》2017年第9期919-922,共4页Journal of Pathogen Biology

基　　金：大连医科大学基础医学学科首批"青年骨干教师助飞项目"

摘　　要：肝吸虫病是我国目前最严重的食源性寄生虫病,肝吸虫感染被世界卫生组织下属机构国际癌症研究中心(IARC)确定为Ⅰ类致癌因素,胆管癌是肝吸虫感染的严重后果且预后较差。本文对肝吸虫感染致胆管癌的发病机制研究进展进行了综述。Liver fluke disease is currently China＇s most serious foodborne parasitic disease.Liver fluke infection was recognized as a group I carcinogen by the International Agency for Research on Cancer（IARC）.Cholangiocarcinoma is a serious consequence of the infection with a poor prognosis.This paper reviews research on the pathogenesis of cholangiocarcinoma caused by liver fluke infection.

关 键 词：华支睾吸虫 胆管癌 发病机制 综述 

分 类 号：R383.22[医药卫生—医学寄生虫学]