钆对比剂在3D-SPACE序列术前评估垂体瘤中的应用  

Diagnosis of Pituitary Adenoma by Contrast Enhanced 3D-SPACE Sequence

作　　者：诸毓文 杨忠[2] 吴越[2] 姚振威[2] ZHU Yu-wen YANG Zhong WU Yue YAO Zhen-wei(Department of Radiology, Shanghai Municipal Hospital of of Traditional Chinese Medicine Department of Radiology, Huashan Hospital, Fudan University)

机构地区：[1]上海中医药大学附属市中医院 [2]复旦大学附属华山医院

出　　处：《中国医学计算机成像杂志》2017年第5期402-406,共5页Chinese Computed Medical Imaging

摘　　要：目的:分析比较增强后3D-SPACE在垂体瘤诊断中的作用,以期优化垂体瘤术前MR评估体系。方法:回顾性分析垂体大腺瘤及ACTH型垂体瘤增强T1-SE、增强3D-SPACE扫描图像,评估两侧海绵窦侵袭情况以及微腺瘤的定位,术前评估结果与手术结果进行分析比较。结果:(1)增强SPACE序列在垂体瘤边界的显示以及海绵窦侵袭性的诊断中都优于T1-SE序列图像(灵敏度81.8 vs.72.7%;特异度86.2vs.65.6%,P<0.05;准确度85.0%vs.67.5%);(2)单独根据T1-SE序列共检出52.4%的ACTH型垂体微腺瘤,结合增强T1-SE及SAPCE序列共检出病灶81.0%。结论:增强后3D-SPACE序列在垂体瘤术前评估其边界、侵袭性及微腺瘤的检出均有重要的诊断价值。Purpose： To analyze the value of preoperative contrast enhanced （CE） 3D-SPACE sequence in diagnosis of pituitary adenoma. Methods： ① CE T1-SE and 3D-SPACE images of pituitary adenoma （〉1cm） and ACTH pituitary microadenoma were retrospectively analyzed. The invasion of cavernous sinus and the microadenoma localization were evaluated on both sequences. Results：① CE 3D-SPACE was superior to T1-SE sequence in assessment of tumor edge and cavernous sinus invasion, the specificity was 86.2% and 65.6 %, P〈0.05, and the accuracy was 85.0 and 67.5%, P〈0.05. ② CE T1-SE sequence was able to identify ACTH microadenomas in 52.4% cases, which was significantly lower than that of CE T1-SE and 3D-SPACE （81.0%）. Conclusion： CE 3D-SPACE sequence takes an important role in evaluating the characteristics of pituitary maeroadenoma and detecting microadenoma preoperatively.

关 键 词：垂体瘤 磁共振成像 增强3D-SPACE序列 

分 类 号：R445.2[医药卫生—影像医学与核医学]