山海丹颗粒治疗冠心病心绞痛的疗效  

Therapeutic Effect of Shanhaidan Granules on Coronary Heart Disease with Angina Pectoris

作　　者：陈绍成[1] 

机构地区：[1]博罗县人民医院内科,广东博罗516100

出　　处：《实用临床医学（江西）》2017年第6期13-15,共3页Practical Clinical Medicine

摘　　要：目的探讨山海丹颗粒治疗冠心病心绞痛(CHD-AP)的临床疗效。方法将58例CHD-AP患者按随机数字表法分为2组:观察组30例,给予山海丹颗粒治疗;对照组28例,给予丹参舒心胶囊治疗。观察2组治疗前、治疗12周后AP发作频率、AP持续时间,左室舒张早期血流速度峰值(E峰)、左室舒张晚期血流速度峰值(A峰)、E/A比值及中医证候疗效、心电图疗效。结果观察组中医证候分析后总有效率、心电图检测后总有效率均明显高于对照组(93.33%比75.00%、86.66%比64.29%,均P<0.05)。与对照组比较,观察组治疗12周后AP发作频率减少,AP持续时间缩短,E峰降低,A峰升高,E/A比值降低(均P<0.05)。结论山海丹颗粒治疗CHD-AP具有较好的疗效,能够有效缓解患者的AP症状,改善左室舒张功能。Objective To explore the clinical effect of Shanhaidan granules on coronary heart disease with angina pectoris（CHD-AP）.Methods Fifty-eight patients with CHD-AP were randomly assigned to receive either Shanhaidan granules（observation group,n=30）or Danshen Shuxin capsules（control group,n=28）.The frequency and duration of AP,left ventricular early diastolic peak velocity（E peak）,left ventricular late diastolic peak velocity（A peak）and E/A ratio were observed before and after 12 weeks of treatment.Results TCM syndrome analysis and ECG examination respectively showed that the total effective rates in observation group were significantly higher than those in control group（93.33% vs 75.00%and 86.66% vs 64.29%,P〈0.05,respectively）.In addition,compared with control group,AP frequency,AP duration,E peak and E/A ratio decreased but A peak increased in observation group after 12 weeks of treatment（P〈0.05）.Conclusion Shanhaidan granules can effectively alleviate AP and improve left ventricular diastolic function in patients with CHD-AP.

关 键 词：冠心病 心绞痛 山海丹颗粒 丹参舒心胶囊 疗效 

分 类 号：R541.4[医药卫生—心血管疾病] R286[医药卫生—内科学]